ArticleLa Radiologia medica2013
Hepatic nodular regenerative lesions in patients with hereditary haemorrhagic telangiectasia: computed tomography and magnetic resonance findings.
Article in La Radiologia medica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Case Report: Rare Acute Abdomen: Focal Nodular Hyperplasia With Spontaneous Rupture.Frontiers in oncology · 2022Article
- The Role of Liver Imaging in Hereditary Hemorrhagic Telangiectasia.Journal of clinical medicine · 2020Review
- Hereditary hemorrhagic telangiectasia: how to efficiently detect hepatic abnormalities using ultrasonography.Journal of medical ultrasonics (2001) · 2020Review
- Spider Telangiectases and Palmar Erythema as Harbingers of Structural Liver Changes in Three Breast Cancer Patients on Ado-trastuzumab Emtansine.The Journal of clinical and aesthetic dermatology · 2019Article
- Hepatocellular Carcinoma in a Patient with Hereditary Hemorrhagic Telangiectasia.Internal medicine (Tokyo, Japan) · 2018Article
- Hepatocellular nodules in vascular liver diseases.Virchows Archiv : an international journal of pathology · 2018Review
- Hepatic angio-sarcoma: An unusual source of intra-hepatic bleeding.International journal of surgery case reports · 2014Article
- Intrahepatic periportal high intensity on hepatobiliary phase images of Gd-EOB-DTPA-enhanced MRI: imaging findings and prevalence in various hepatobiliary diseases.Japanese journal of radiology · 2013Article
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Authors and funding
9 authors.
Funding
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Abstract
purposeThis study was done to evaluate the prevalence of regenerative hepatic nodules in patients with hereditary haemorrhagic telangiectasia (HHT). MATERIALS AND
methodsBetween February 2001 and December 2010, 171 consecutive HHT patients (95 men and 76 women) were studied with triphasic multidetector computed tomography (MDCT) in 91 cases, magnetic resonance imaging (MRI) in 34 cases and both in the remaining 46 cases. The presence of diffuse vascular abnormalities and focal liver lesions were recorded.
resultsHepatic arteriovenous malformations (HAVMs) were found in 126/171 (74%) patients. Arteriovenous shunts were found in 24/171 (14%) cases, arterioportal shunts in 52/171 (30%), mixed shunts in 26/171 (15%), telangiectases in 84/171 (49%) and transient hepatic attenuation differences (THADs) in 70/171 (41%). Hepatic nodular lesions were found in 6/171 (3.5%) patients (three men; three women). In 5/6 cases, vascular abnormalities were also evident. Two patients had a single lesion; four had multiple lesions. No lesion showed a central scar.
conclusionsHyperenhancing hepatic regenerative lesions have a high prevalence in HHT patients, representing the response of liver parenchyma to hypoperfusion caused by HAVMs. These lesions are often multiple and may lead to nodular regenerative hyperplasia.
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