ArticleNature methods2012
Combined RNAi and localization for functionally dissecting long noncoding RNAs.
Article in Nature methods, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- The long noncoding RNA MAPKAPK5-AS1 promotes the formation of hepatitis B virus cccDNA by modulating the expression of NABP1.Virulence · 2026Article
- Profiling mitochondria-polyribosome lncRNAs associated with pluripotency.Scientific data · 2023Article
- The pluripotent factor OCT4A enhances the self-renewal of human dental pulp stem cells by targeting lncRNA FTX in an LPS-induced inflammatory microenvironment.Stem cell research & therapy · 2023Article
- Long noncoding RNARNA biology · 2021Article
- Decoding LncRNAs.Cancers · 2021Review
- Mutant non-coding RNA resource in mouse embryonic stem cells.Disease models & mechanisms · 2021Article
- Research progress on the interactions between long non-coding RNAs and microRNAs in human cancer.Oncology letters · 2020Review
- Novel Approaches to Profile Functional Long Noncoding RNAs Associated with Stem Cell Pluripotency.Current genomics · 2020Review
- lncRedibly versatile: biochemical and biological functions of long noncoding RNAs.The Biochemical journal · 2019Review
- Platforms for Investigating LncRNA Functions.SLAS technology · 2018Review
- Capturing functional long non-coding RNAs through integrating large-scale causal relations from gene perturbation experiments.EBioMedicine · 2018Article
- Noncoding RNAs in the Regulation of Pluripotency and Reprogramming.Stem cell reviews and reports · 2018Review
- The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells.PloS one · 2018Article
- State of the art technologies to explore long non-coding RNAs in cancer.Journal of cellular and molecular medicine · 2017Review
- Identification and characterization of long intergenic noncoding RNAs in bovine mammary glands.BMC genomics · 2017Article
- The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells.Scientific reports · 2017Article
- The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.Nucleic acids research · 2017Article
- The essentiality of non-coding RNAs in cell reprogramming.Non-coding RNA research · 2017Review
- Regulatory Roles of Long Non-Coding RNAs in the Central Nervous System and Associated Neurodegenerative Diseases.Frontiers in cellular neuroscience · 2017Review
- Long non-coding RNAs in corticogenesis: deciphering the non-coding code of the brain.The EMBO journal · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whereas methods to comprehensively study cellular roles of protein-coding genes are available, techniques to systematically investigate long noncoding RNAs (lncRNAs), which have been implicated in diverse biological pathways, are limited. Here we report combined knockdown and localization analysis of noncoding RNAs (c-KLAN) that merges functional characterization and localization approaches to study lncRNAs. Using this technique we identified transcripts that regulate mouse embryonic stem cell identity.
Indexed as
Identifiers
22327834What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.