ReviewCurrent opinion in HIV and AIDS2012
The effects of schistosomiasis on HIV/AIDS infection, progression and transmission.
Review in Current opinion in HIV and AIDS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 6 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Association of schistosomiasis and HIV infections: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Pooled it
- Interactions ofThe American journal of tropical medicine and hygiene · 2020Pooled it
- Considering treatment of male genital schistosomiasis as a tool for future HIV prevention: a systematic review.International journal of public health · 2015Pooled it
- The roles of water, sanitation and hygiene in reducing schistosomiasis: a review.Parasites & vectors · 2015Pooled it
- The relationship between water, sanitation and schistosomiasis: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2014Pooled it
- Neglected tropical diseases: survey and geometry of randomised evidence.BMJ (Clinical research ed.) · 2012Pooled it
- Trial
- Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways.Nature communications · 2019Trial
- Mainstreaming female genital schistosomiasis to ensure it is not neglected among the neglected tropical diseases.Parasitology · 2025Review
- Epidemiological, clinical and immunological features of Schistosoma spp., Stronglyoides stercoralis and Taenia spp. infections in Ghanaian HIV patients.European journal of microbiology & immunology · 2025Article
- Antischistosomal Potential of Animal-Derived Natural Products and Compounds.Microorganisms · 2025Review
- Female Genital Schistosomiasis as a Cause of Tubal Ectopic Pregnancy and Recurrent Pregnancy Loss: A Case Report.Case reports in pathology · 2025Article
- Beyond schistosomiasis: unraveling co-infections and altered immunity.Clinical microbiology reviews · 2024Review
- Article
- Identifying determinants for the seropositive rate of schistosomiasis in Hunan province, China: A multi-scale geographically weighted regression model.PLoS neglected tropical diseases · 2023Article
- Neurocysticercosis and HIV/AIDS co-infection: A scoping review.Tropical medicine & international health : TM & IH · 2021Article
- Schistosomiasis is associated with rectal mucosal inflammation among Kenyan men who have sex with men.International journal of STD & AIDS · 2021Article
- Schistosoma mansoni Infection Is Associated With a Higher Probability of Tuberculosis Disease in HIV-Infected Adults in Kenya.Journal of acquired immune deficiency syndromes (1999) · 2021Article
- Coinfection of HIV-1 withEC microbiology · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThe recent findings pertaining to the public health impact of schistosomiasis on the epidemiology of HIV/AIDS are summarized. RECENT
findingsBoth empiric data and mathematical models support the hypothesis that schistosome infections lead to increased susceptibility to infection with HIV-1, a more rapid progression to disease through more vigorous viral replication and immunosuppression, and a higher likelihood of transmitting the infection to others through both vertical and horizontal routes. Different species of schistosome infection vary in the magnitude of their effects on these mechanisms with Schistosoma haematobium playing a greater role for increased susceptibility and transmission because of its association with urogenital disease. SUMMARY: Schistosomiasis appears to be a cofactor in the spread and progression of HIV/AIDS in areas wherein both diseases are endemic; increased emphasis on treatment of schistosome infections in persons at risk of HIV/AIDS should be pursued.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.