ArticleEcotoxicology (London, England)2012
Cadmium affects toxicokinetics of pyrene in the collembolan Folsomia candida.
Article in Ecotoxicology (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Mutation at Different Sites of Metal Transporter GeneFrontiers in plant science · 2019Article
- The effect of soil pollution with petroleum-derived substances on Porcellio scaber Latr. (Crustacea, Isopoda).Environmental monitoring and assessment · 2018Article
- Antioxidant enzyme activities of Folsomia candida and avoidance of soil metal contamination.Environmental science and pollution research international · 2018Article
- Sublethal effects in Perinereis gualpensis (Polychaeta: Nereididae) exposed to mercury-pyrene sediment mixture observed in a multipolluted estuary.Ecotoxicology (London, England) · 2017Article
- Article
- The effects of two common edible herbs, Ipomoea aquatica and Enhydra fluctuans, on cadmium-induced pathophysiology: a focus on oxidative defence and anti-apoptotic mechanism.Journal of translational medicine · 2015Article
- The use of elements as a substitute for biomass in toxicokinetic studies in small organisms.Ecotoxicology (London, England) · 2013Article
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3 authors.
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Abstract
Since toxicity is time dependent, short-term toxicity tests may overlook mixture effects, because chemical accumulation within an organism takes time. We therefore studied the effects of cadmium on the toxicokinetics of pyrene and its metabolites in the soil-dwelling collembolan Folsomia candida exposed through Lufa 2.2 soil. Single pyrene was rapidly taken up and steady state was reached within the 337-h exposure period. Simultaneous exposure to cadmium significantly decreased the pyrene uptake and elimination rate, resulting in a prolonged half life. Kinetics of the first phase metabolite OH-pyrene was also significantly influenced by cadmium. Cadmium increased the hydroxylation rate of pyrene but slowed down its further metabolization, again resulting in a prolonged half life. We showed that pyrene accumulation and metabolization are significantly influenced by the presence of cadmium. Our results suggest that mixture effects may be dependent on exposure time.
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