ArticleCurrent biology : CB2012
Mechanosensitive channels protect plastids from hypoosmotic stress during normal plant growth.
Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 123 citations in OpenAlex.
- Genome-Wide Identification, Molecular Evolution, and Expression Divergence ofFood science & nutrition · 2025Article
- Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels.Nature cell biology · 2024Article
- Plants distinguish different photoperiods to independently control seasonal flowering and growth.Science (New York, N.Y.) · 2024Article
- Origin, evolution and diversification of plant mechanosensitive channel of small conductance-like (MSL) proteins.BMC plant biology · 2023Article
- Parallel mechanisms detect different photoperiods to independently control seasonal flowering and growth in plants.bioRxiv : the preprint server for biology · 2023Article
- Autophagy regulates plastid reorganization during spermatogenesis in the liverwortFrontiers in plant science · 2023Article
- Molecular response and evolution of plant anion transport systems to abiotic stress.Plant molecular biology · 2022Review
- Entanglement of Arabidopsis Seedlings to a Mesh Substrate under Microgravity Conditions in KIBO on the ISS.Plants (Basel, Switzerland) · 2022Article
- Plant cell mechanobiology: Greater than the sum of its parts.The Plant cell · 2022Review
- Molecular Mechanisms of Plant Responses to Salt Stress.Frontiers in plant science · 2022Review
- Delineating Calcium Signaling Machinery in Plants: Tapping the Potential through Functional Genomics.Current genomics · 2021Review
- A metabolic daylength measurement system mediates winter photoperiodism in plants.Developmental cell · 2021Article
- With an Ear Up against the Wall: An Update on Mechanoperception inPlants (Basel, Switzerland) · 2021Review
- Organelle extensions in plant cells.Plant physiology · 2021Article
- Review
- The gravistimulation-induced very slow CaScientific reports · 2021Article
- Rapid movements in plants.Journal of plant research · 2021Review
- Charged pore-lining residues are required for normal channel kinetics in the eukaryotic mechanosensitive ion channel MSL1.Channels (Austin, Tex.) · 2020Article
- Plant cell wall integrity maintenance in model plants and crop species-relevant cell wall components and underlying guiding principles.Cellular and molecular life sciences : CMLS · 2020Review
- Mechanisms of Plant Responses and Adaptation to Soil Salinity.Innovation (Cambridge (Mass.)) · 2020Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Cellular response to osmotic stress is critical for survival and involves volume control through the regulated transport of osmolytes. Organelles may respond similarly to abrupt changes in cytoplasmic osmolarity. The plastids of the Arabidopsis thaliana leaf epidermis provide a model system for the study of organellar response to osmotic stress within the context of the cell. An Arabidopsis mutant lacking two plastid-localized homologs of the bacteria mechanosensitive channel MscS (MscS-like [MSL] 2 and 3) exhibits large round epidermal plastids that lack dynamic extensions known as stromules. This phenotype is present under normal growth conditions and does not require exposure to extracellular osmotic stress. Here we show that increasing cytoplasmic osmolarity through a genetic lesion known to produce elevated levels of soluble sugars, exogenously providing osmolytes in the growth media, or withholding water rescues the msl2-1 msl3-1 leaf epidermal plastid phenotype, producing plastids that resemble the wild-type in shape and size. Furthermore, the epidermal plastids in msl2-1 msl3-1 leaves undergo rapid and reversible volume and shape changes in response to extracellular hypertonic or hypotonic challenges. We conclude that plastids are under hypoosmotic stress during normal plant growth and dynamic response to this stress requires MSL2 and MSL3.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.