Evidence map›Paper›PMID 22325790›Full record

ArticleProtist2012

Characterization and taxonomic validity of the ciliate Oxytricha trifallax (Class Spirotrichea) based on multiple gene sequences: limitations in identifying genera solely by morphology.

Stephen D Zoller, Robert L Hammersmith, Estienne C Swart, Brian P Higgins, Thomas G Doak, Glenn Herrick, Laura F Landweber

Abstract read
In one paragraph

Article in Protist, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Non-model model organisms.BMC biology · 2017
    Article
  4. What Is a Genome?PLoS genetics · 2016
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephen D ZollerDepartment of Ecology and Evolutionary Biology, Princeton University, NJ 08544, USA.
Robert L Hammersmith
Estienne C Swart
Brian P Higgins
Thomas G Doak
Glenn Herrick
Laura F Landweber

Funding

UNDERSTANDING COMPLEX GENE EDITING SYSTEMS IN PROTISTSR01GM059708 · NIGMS · PRINCETON UNIVERSITY · PI LANDWEBER, LAURA F · 1999 to 2016
$4.4M
SOMATIC GENOME ALTERATIONS IN OXYTRICHA FALLAXR01GM025203 · NIGMS · UNIVERSITY OF UTAH · PI HERRICK, GLENN A · 1985 to 2000
$188k
NIGMS NIH HHS GM25203NIGMS NIH HHS GM59708NIGMS NIH HHS R01 GM059708
6 · The paper itself

Abstract

Oxytricha trifallax - an established model organism for studying genome rearrangements, chromosome structure, scrambled genes, RNA-mediated epigenetic inheritance, and other phenomena - has been the subject of a nomenclature controversy for several years. Originally isolated as a sibling species of O. fallax, O. trifallax was reclassified in 1999 as Sterkiella histriomuscorum, a previously identified species, based on morphological similarity. The proper identification of O. trifallax is crucial to resolve in order to prevent confusion in both the comparative genomics and the general scientific communities. We analyzed nine conserved nuclear gene sequences between the two given species and several related ciliates. Phylogenetic analyses suggest that O. trifallax and a bona fide S. histriomuscorum have accumulated significant evolutionary divergence from each other relative to other ciliates such that they should be unequivocally classified as separate species. We also describe the original isolation of O. trifallax, including its comparison to O. fallax, and we provide criteria to identify future isolates of O. trifallax.

Indexed as

PhylogenyCluster AnalysisDNA, ProtozoanMolecular Sequence DataOxytrichaSequence Analysis, DNADNA, Protozoan

Identifiers

PMID22325790
PMCPMC3433844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.