ArticleJournal of psychosomatic research2012
Comparison of two depression measures for predicting stroke outcomes.
Article in Journal of psychosomatic research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of depression on stroke outcomes among stroke survivors: Systematic review and meta-analysis.PloS one · 2023Pooled it
- Improving Quality of Life and Depression After Stroke Through Telerehabilitation.The American journal of occupational therapy : official publication of the American Occupational Therapy AssociationTrial
- Poor Sleep Health Early After Stroke is Associated with Lower Quality of Life Later After Stroke.medRxiv : the preprint server for health sciences · 2025Article
- Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study.Scientific reports · 2025Article
- The Moderating Role of Motivation in the Real-Time Associations of Fatigue, Cognitive Complaints, and Pain With Depressed Mood Among Stroke Survivors: An Ecological Momentary Assessment Study.Archives of physical medicine and rehabilitation · 2023Article
- Early-Onset Depression in Stroke Patients: Effects on Unfavorable Outcome 5 Years Post-stroke.Frontiers in psychiatry · 2021Article
- Optimizing functional outcome endpoints for stroke recovery studies.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Review
- Efficacy and tolerability of pharmacotherapy for post-stroke depression: a network meta-analysis.Oncotarget · 2018Article
- Comparative efficacy and acceptability of antidepressant treatment in poststroke depression: a multiple-treatments meta-analysis.BMJ open · 2017Article
- Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke.Translational psychiatry · 2016Article
- Exploring a need for improved preclinical models of post-stroke depression.Neural regeneration research · 2016Article
- Age, subjective stress, and depression after ischemic stroke.Journal of behavioral medicine · 2016Article
- Of mice and men: modelling post-stroke depression experimentally.British journal of pharmacology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
objectivesLittle is known about the effect of lifetime history of depression on ischemic stroke outcomes. This study compared a measure of current symptoms of depression at the time of the stroke and a measure of lifetime history of depression for their ability to predict quality of life and functioning at 3 and 12 months after stroke.
methodsA cohort of 460 ischemic stroke patients from the 2005 Greater Cincinnati/North Kentucky Stroke Study was assessed within 2 weeks of the stroke, including the 10-item Center for Epidemiological Studies Depression Scale (CESD) for current symptoms of depression. Lifetime history of depression was also assessed by a 2-question measure at 3 and 12 months after stroke. Two outcome measures, Stroke Specific Quality of Life (SSQOL) and the modified Rankin Scale (mRS) to assess functional status, were also collected at 3 and 12 months.
resultsOf the 322 survivors included in the analysis, 52.2% reported depression on at least one measure. Both current symptoms and lifetime history of depression predicted poor functional outcomes and poor quality of life at 3 and 12 months, after adjustment for age, race, sex, prior stroke, baseline functional status, and stroke severity. The combination of depression measures was a better predictor of poor outcomes than either measure alone.
conclusionDepression by either measure was a frequent, substantial, and independent predictor of poor outcomes at 3 and 12 months after stroke. Stroke outcomes studies should further examine the predictive value of assessing both depressive symptoms at the time of the stroke and lifetime history of depression.
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