ArticleEnvironmental science & technology2012
Providing the missing link: the exposure science ontology ExO.
Article in Environmental science & technology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Representation of chemistry transport models simulations using knowledge graphs.Journal of cheminformatics · 2025Article
- The Environmental Conditions, Treatments, and Exposures Ontology (ECTO): connecting toxicology and exposure to human health and beyond.Journal of biomedical semantics · 2023Article
- Environmental exposures in machine learning and data mining approaches to diabetes etiology: A scoping review.Artificial intelligence in medicine · 2023Article
- Exposure forecasting - ExpoCast - for data-poor chemicals in commerce and the environment.Journal of exposure science & environmental epidemiology · 2022Review
- Development of the International Classification of Diseases Ontology (ICDO) and its application for COVID-19 diagnostic data analysis.BMC bioinformatics · 2021Article
- Catalyzing Knowledge-Driven Discovery in Environmental Health Sciences through a Community-Driven Harmonized Language.International journal of environmental research and public health · 2021Article
- Alleviating Environmental Health Disparities Through Community Science and Data Integration.Frontiers in sustainable food systems · 2021Article
- Semantic standards of external exposome data.Environmental research · 2021Review
- Why and how to engage expert stakeholders in ontology development: insights from social and behavioural sciences.Journal of biomedical semantics · 2021Review
- Comparative Toxicogenomics Database (CTD): update 2021.Nucleic acids research · 2021Article
- Community Approaches for Integrating Environmental Exposures into Human Models of Disease.Environmental health perspectives · 2020Article
- Advancing systematic-review methodology in exposure science for environmental health decision making.Journal of exposure science & environmental epidemiology · 2020Article
- Enhancing life cycle chemical exposure assessment through ontology modeling.The Science of the total environment · 2020Article
- A Quantitative Source-to-Outcome Case Study To Demonstrate the Integration of Human Health and Ecological End Points Using the Aggregate Exposure Pathway and Adverse Outcome Pathway Frameworks.Environmental science & technology · 2019Article
- Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure Pathways.Environmental science & technology · 2019Article
- The Comparative Toxicogenomics Database: update 2019.Nucleic acids research · 2019Article
- Embracing microbes in exposure science.Journal of exposure science & environmental epidemiology · 2019Article
- Refining the aggregate exposure pathway.Environmental science. Processes & impacts · 2018Article
- Accessing an Expanded Exposure Science Module at the Comparative Toxicogenomics Database.Environmental health perspectives · 2018Article
- The CAIRR Pipeline for Submitting Standards-Compliant B and T Cell Receptor Repertoire Sequencing Studies to the National Center for Biotechnology Information Repositories.Frontiers in immunology · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Environmental health information resources lack exposure data required to translate molecular insights, elucidate environmental contributions to diseases, and assess human health and ecological risks. We report development of an Exposure Ontology, ExO, designed to address this information gap by facilitating centralization and integration of exposure data. Major concepts were defined and the ontology drafted and evaluated by a working group of exposure scientists and other ontology and database experts. The resulting major concepts forming the basis for the ontology are "exposure stressor", "exposure receptor", "exposure event", and "exposure outcome". Although design of the first version of ExO focused on human exposure to chemicals, we anticipate expansion by the scientific community to address exposures of human and ecological receptors to the full suite of environmental stressors. Like other widely used ontologies, ExO is intended to link exposure science and diverse environmental health disciplines including toxicology, epidemiology, disease surveillance, and epigenetics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.