ReviewAlimentary pharmacology & therapeutics2012
Review article: coeliac disease, new approaches to therapy.
Review in Alimentary pharmacology & therapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Search for atoxic cereals: a single blind, cross-over study on the safety of a single dose of Triticum monococcum, in patients with celiac disease.BMC gastroenterology · 2013Trial
- Plasma Citrulline in the Diagnosis and Follow-Up of Celiac Disease.Children (Basel, Switzerland) · 2024Article
- Celiac disease: Pathogenesis, disease management and new insights into the herbal-based treatments.Narra J · 2023Review
- Novel Therapeutic Strategies for Celiac Disease.Middle East journal of digestive diseases · 2020Review
- Cognitive Impairment in Coeliac Disease with Respect to Disease Duration and Gluten-Free Diet Adherence: A Pilot Study.Nutrients · 2020Article
- Ex vivo immunomodulatory effect of ethanolic extract of propolis during Celiac Disease: involvement of nitric oxide pathway.Inflammopharmacology · 2018Article
- Genetic and environmental factors affecting the expression of α-gliadin canonical epitopes involved in celiac disease in a wide collection of spelt (Triticum aestivum ssp. spelta) cultivars and landraces.BMC plant biology · 2018Article
- The production of a recombinant tandem single chain fragment variable capable of binding prolamins triggering celiac disease.BMC biotechnology · 2018Article
- The In Vitro Effects of Enzymatic Digested Gliadin on the Functionality of the Autophagy Process.International journal of molecular sciences · 2018Article
- Article
- Celiac disease: From pathophysiology to treatment.World journal of gastrointestinal pathophysiology · 2017Review
- Celiac Disease in India - Status Update.Indian journal of pediatrics · 2017Article
- Development of TaqMan probes targeting the four major celiac disease epitopes found in α-gliadin sequences of spelt (Plant methods · 2017Article
- The potential utility of tight junction regulation in celiac disease: focus on larazotide acetate.Therapeutic advances in gastroenterology · 2016Review
- Molecular diversity of α-gliadin expressed genes in genetically contrasted spelt (Molecular breeding : new strategies in plant improvement · 2016Article
- Support for patients with celiac disease: A literature review.United European gastroenterology journal · 2015Review
- Tax-deductible provisions for gluten-free diet in Canada compared with systems for gluten-free diet coverage available in various countries.Canadian journal of gastroenterology & hepatology · 2015Review
- Specific nongluten proteins of wheat are novel target antigens in celiac disease humoral response.Journal of proteome research · 2015Article
- Diversity of oat varieties in eliciting the early inflammatory events in celiac disease.European journal of nutrition · 2014Article
- Inflammatory bowel disease and celiac disease: overlaps and differences.World journal of gastroenterology · 2014Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundCoeliac disease is managed by life-long gluten withdrawal from the diet. However, strict adherence to a gluten-free diet is difficult and is not always effective. Novel therapeutic approaches are needed to supplement or even replace the dietary treatment.
aimTo review recent advances in new therapeutic options for coeliac disease.
methodsA literature search was performed on MEDLINE, EMBASE, Web of Science, Scopus, DDW.org and ClinicalTrials.gov for English articles and abstracts. The search terms used included, but not limited to, 'Celiac disease', 'new', 'novel', 'Advances', 'alternatives' and 'Drug therapy'. The cited articles were selected based on the relevancy to the review objective.
resultsSeveral new therapeutic approaches for coeliac disease are currently under development by targeting its underlying pathogenesis. Alternative therapies range from reproduction of harmless wheat strains to immunomodulatory approaches. Some of these therapies such as enzymatic cleavage of gluten and permeability inhibitors have shown promise in clinical studies.
conclusionsGluten-free diet is still the only practical treatment for patients with coeliac disease. Novel strategies provide promise of alternative adjunctive approaches to diet restriction alone for patients with this disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.