SynthesisCurrent hypertension reports2012
Retinal arteriolar diameter and the prevalence and incidence of hypertension: a systematic review and meta-analysis of their association.
Synthesis in Current hypertension reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Retinal vascular caliber and the development of hypertension: a meta-analysis of individual participant data.Journal of hypertension · 2014Pooled it
- Randomized 20-year infancy-onset dietary intervention, life-long cardiovascular risk factors and retinal microvasculature.European heart journal · 2024Trial
- High-salt intake affects retinal vascular tortuosity in healthy males: an exploratory randomized cross-over trial.Scientific reports · 2021Trial
- Retinal image-based cardiovascular risk prediction using AI-CRS: a multi-modal deep learning framework.International ophthalmology · 2026Article
- Retinal Imaging as a Window into Cardiovascular Health: Towards Harnessing Retinal Analytics for Precision Cardiovascular Medicine.Journal of cardiovascular development and disease · 2025Review
- Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset.Translational vision science & technology · 2025Article
- Retinal oculomics and risk of incident aortic aneurysm and aortic adverse events: a population-based cohort study.International journal of surgery (London, England) · 2025Article
- Retinal Arteriovenous Information Improves the Prediction Accuracy of Deep Learning-Based baPWV Index From Color Fundus Photographs.Investigative ophthalmology & visual science · 2025Article
- Retinal Imaging-Based Oculomics: Artificial Intelligence as a Tool in the Diagnosis of Cardiovascular and Metabolic Diseases.Biomedicines · 2024Review
- Non-Invasive Retinal Vessel Analysis as a Predictor for Cardiovascular Disease.Journal of personalized medicine · 2024Review
- Retinal vascular changes and arterial stiffness during 8-month isolation and confinement: the SIRIUS-21 space analog mission.Frontiers in physiology · 2024Article
- A deep learning system for retinal vessel calibre improves cardiovascular risk prediction in Asians with chronic kidney disease.Clinical kidney journal · 2023Article
- The Effect of Bariatric Surgery on Microvascular Structure and Function, Peripheral Pressure Waveform and General Cardiovascular Risk: A Longitudinal Study.Journal of clinical medicine · 2023Article
- Association of Cardiovascular Disease with Retinopathy of Prematurity.Ophthalmic epidemiology · 2023Article
- Acute effects of caffeine and glucose intake on retinal vessel calibres in healthy volunteers.International ophthalmology · 2023Article
- Impact of Arterial Hypertension on the Eye: A Review of the Pathogenesis, Diagnostic Methods, and Treatment of Hypertensive Retinopathy.Medical science monitor : international medical journal of experimental and clinical research · 2022Review
- MSGANet-RAV: A multiscale guided attention network for artery-vein segmentation and classification from optic disc and retinal images.Journal of optometry · 2022Article
- Retinal vessel diameters, flicker-induced retinal vasodilation and retinal oxygen saturation in high- and low-risk pregnancy.Acta ophthalmologica · 2021Article
- The Impact of Chronic Heart Failure on Retinal Vessel Density Assessed by Optical Coherence Tomography Angiography in Children with Dilated Cardiomyopathy.Journal of clinical medicine · 2021Article
- A Deep Learning Architecture for Vascular Area Measurement in Fundus Images.Ophthalmology science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension is a leading risk factor for increased mortality and morbidity. One pathogenesis mechanism, increased peripheral vascular resistance, relates to arteriolar diameter. Retinal arterioles, visualized and measured through retinal images, provide an insight into the microvascular structure and hints of peripheral vascular resistance. Multiple studies have demonstrated an inverse association between increasing blood pressure and narrowing retinal arteriolar diameter. This systematic review summarizes the currently available evidence from cross-sectional and longitudinal population-based studies that have investigated this association. A meta-analysis of five cross-sectional studies (19,633 adults) provided an averaged regression coefficient of -3.07 μm (95% CI, -3.73, -2.40) narrowing in retinal arteriolar diameter for every 10 mm Hg increase in mean arterial blood pressure. Four longitudinal studies (6,247 adults) with follow-up periods ranging from 3 to 7 years consistently showed that generalized retinal arteriolar narrowing (defined as the lowest tertile, quartile, or quintile in the population) was associated with an increased risk of incident hypertension (meta-analysis odds ratio 1.91; 95% CI, 1.56-2.34).
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.