ArticleMolecular plant pathology2012
MoSwi6, an APSES family transcription factor, interacts with MoMps1 and is required for hyphal and conidial morphogenesis, appressorial function and pathogenicity of Magnaporthe oryzae.
Article in Molecular plant pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
69 citing papers in PubMed, 127 citations in OpenAlex.
- Article
- MoMtg1 Acts as a Novel Transcriptional Repressor of MoSwi6 During Appressorium-Mediated Penetration in the Rice Blast Fungus.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The APSES transcription factor Swi6B upregulatesApplied and environmental microbiology · 2025Article
- CWI-MAPKs Regulate the Formation of Hyphopodia Required for Virulence in Ceratocystis fimbriata.Molecular plant pathology · 2025Article
- Decapeptide Inducer Promotes the Conidiation of PhytopathogenicInternational journal of molecular sciences · 2025Article
- The GCN4-Swi6B module mediates low nitrogen-induced cell wall remodeling inApplied and environmental microbiology · 2025Article
- Combinatorial Targeting of Common Docking and ATP Binding Sites on Mps1 MAPK for Management of Pathogenic Fungi.Journal of agricultural and food chemistry · 2024Article
- Development of Green Fluorescent Protein-Tagged Strains ofMicroorganisms · 2024Article
- AfSwi6 Regulates the Stress Response, Chlamydospore Production, and Pathogenicity in the Nematode-Trapping FungusMicroorganisms · 2024Article
- Article
- The APSES Transcription Factor SsStuA Regulating Cell Wall Integrity Is Essential for Sclerotia Formation and Pathogenicity inJournal of fungi (Basel, Switzerland) · 2024Article
- The MoLfa1 Protein Regulates Fungal Development and Septin Ring Formation inInternational journal of molecular sciences · 2024Article
- Two zinc finger proteins, VdZFP1 and VdZFP2, interact with VdCmr1 to promote melanized microsclerotia development and stress tolerance in Verticillium dahliae.BMC biology · 2023Article
- The Mechanism of Transcription Factor Swi6 in Regulating Growth and Pathogenicity ofMicroorganisms · 2023Article
- MoCbp7, a Novel Calcineurin B Subunit-Binding Protein, Is Involved in the Calcium Signaling Pathway and Regulates Fungal Development, Virulence, and ER Homeostasis inInternational journal of molecular sciences · 2023Article
- Article
- Contribution of the Tyrosinase (MoTyr) to Melanin Synthesis, Conidiogenesis, Appressorium Development, and Pathogenicity inJournal of fungi (Basel, Switzerland) · 2023Article
- The Devastating Rice Blast Airborne PathogenPathogens (Basel, Switzerland) · 2023Review
- MoMih1 is indispensable for asexual development, cell wall integrity, and pathogenicity ofFrontiers in plant science · 2023Article
- PKC-SWI6 signaling regulates asexual development, cell wall integrity, stress response, and lifestyle transition in the nematode-trapping fungus Arthrobotrys oligospora.Science China. Life sciences · 2022Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
The Magnaporthe oryzae mitogen-activated protein kinase (MAPK) MoMps1 plays a critical role in the regulation of various developmental processes, including cell wall integrity, stress responses and pathogenicity. To identify potential effectors of MoMps1, we characterized the function of MoSwi6, a homologue of Saccharomyces cerevisiae Swi6 downstream of MAPK Slt2 signalling. MoSwi6 interacted with MoMps1 both in vivo and in vitro, suggesting a possible functional link analogous to Swi6-Slt2 in S. cerevisiae. Targeted gene disruption of MoSWI6 resulted in multiple developmental defects, including reduced hyphal growth, abnormal formation of conidia and appressoria, and impaired appressorium function. The reduction in appressorial turgor pressure also contributed to an attenuation of pathogenicity. The ΔMoswi6 mutant also displayed a defect in cell wall integrity, was hypersensitive to oxidative stress, and showed a significant reduction in transcription and activity of extracellular enzymes, including peroxidases and laccases. Collectively, these roles are similar to those of MoMps1, confirming that MoSwi6 functions in the MoMps1 pathway to govern growth, development and full pathogenicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.