Evidence map›Paper›PMID 22321019›Full record

ReviewAddiction (Abingdon, England)2012

Comparative dynamics of four smoking withdrawal symptom scales.

Harold S Javitz, Caryn Lerman, Gary E Swan

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Addiction (Abingdon, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Varenicline Over-The-Counter Trial on Efficacy and Safety.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Trial
  2. Trial
  3. Evaluating the temporal relationships between withdrawal symptoms and smoking relapse.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019
    Trial
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  7. Article
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  12. Cigarette smoking and ADHD: An examination of prognostically relevant smoking behaviors among adolescents and young adults.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2016
    Article
  13. Article
  14. Article
  15. Clinical significance of early smoking withdrawal effects and their relationships with nicotine metabolism: preliminary results from a pilot study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Harold S JavitzCenter for Health Sciences, SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA. harold.javitz@sri.com
Caryn Lerman
Gary E Swan
Oklahoma State University Center for Health Sciences · USSRI International · USUniversity of Pennsylvania · US

Funding

University of Toronto Coordinating Genetics Core & Clinical Trial SiteU01DA020830 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI SWAN, GARY E · 2005 to 2014
$22.4M
Neuroimaging Abstinence and Medication ResponseP50CA143187 · NCI · UNIVERSITY OF PENNSYLVANIA · PI AUDRAIN-MCGOVERN, JANET E · 2009 to 2013
$8.6M
BIOBEHAVIORAL LUNG CANCER PREVENTION PROGRAMR01CA063562 · NCI · UNIVERSITY OF PENNSYLVANIA · PI LERMAN, CARYN · 1993 to 2004
$2.7M
NCI NIH HHS P50 CA143187NCI NIH HHS P50CA143187NCI NIH HHS R01 CA063562NCI NIH HHS R01CA63562NIDA NIH HHS U01 DA020830
6 · The paper itself

Abstract

aimsTo examine the association of person-specific trajectories of withdrawal symptoms of urge-to-smoke, negative affect, physical symptoms and hunger during the first 7 days after smoking cessation with abstinence at end of treatment (EOT) and at 6 months.

designHierarchical linear modeling (HLM) was used to model person-specific trajectory parameters (level, slope, curvature and volatility) for withdrawal symptoms.

settingUniversity-based smoking cessation trials.

participantsTreatment-seeking smokers in clinical trials of transdermal nicotine versus nicotine spray (n = 514) and bupropion versus placebo (n = 421). MEASUREMENTS: Self-reported withdrawal symptoms for 7 days after the planned quit date, and 7-day point prevalence and continuous abstinence at EOT and 6 months.

findingsIn regressions that included trajectory parameters for one group of withdrawal symptoms, both urge-to-smoke and negative affect were predictive of abstinence while physical symptoms and hunger were generally not predictive. In stepwise regressions that included the complete set of trajectory parameters across withdrawal symptoms (for urge-to-smoke, negative affect, physical symptoms and hunger), with a single exception only the trajectory parameters for urge-to-smoke were predictive. Area under the receiver operator characteristic curve was 0.594 for covariates alone, and 0.670 for covariates plus urge-to-smoke trajectory parameters.

conclusionsAmong a number of different withdrawal symptoms (urge-to-smoke, negative affect, physical symptoms and hunger) urge-to-smoke trajectory parameters (level, slope and volatility) over the first 7 days of smoking cessation show the strongest prediction of both short- and long-term relapse. Other withdrawal symptoms increase the predictive ability by negligible amounts.

Indexed as

Psychiatric Status Rating ScalesSmoking CessationAdministration, InhalationBupropionDopamine Uptake InhibitorsDouble-Blind MethodFemaleHumansHungerMaleMiddle AgedMotivationRandomized Controlled Trials as TopicRecurrenceSelf ReportSubstance Withdrawal SyndromeBupropionDopamine Uptake Inhibitors

Identifiers

PMID22321019
PMCPMC3394903
OpenAlexW1491868008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.