ArticleInternational journal of andrology2012
Gonadal and extragonadal germ cell tumours in the United States, 1973-2007.
Article in International journal of andrology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 2 of them syntheses that pooled it.
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Who cites it
74 citing papers in PubMed, 2 syntheses or guidelines pooled it, 174 citations in OpenAlex.
- How to classify, diagnose, treat and follow-up extragonadal germ cell tumors? A systematic review of available evidence.World journal of urology · 2022Pooled it
- Meta-analysis identifies four new loci associated with testicular germ cell tumor.Nature genetics · 2013Pooled it
- Successful Treatment of Primary Mediastinal Seminoma With Radiotherapy Following Chemotherapy Under a Bloodless Treatment Policy Based on Patient's Religious Sentiments.IJU case reports · 2026Article
- Extracranial, Extragonadal Germ Cell Tumors: A Multicenter Australian Case Series.Asia-Pacific journal of clinical oncology · 2026Observational
- Comparative Molecular and Genetic Landscape of Gonadal Germ Cell Tumors: Insights from Testicular and Ovarian Neoplasms.Cancers · 2026Review
- Primary prostatic seminoma: a rare case report and structured literature review highlighting tumor marker discordance.Therapeutic advances in medical oncology · 2026Article
- Gross hematuria secondary to vesicular varices: an unusual long-term sequela of inferior vena cava ligation and resection case report.Urology case reports · 2025Article
- Long-term survival and prognostic factors in extragonadal germ cell tumors: a 30-year experience at a single institution.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- Anemic retinopathy as the presenting symptom of a mediastinal germ cell tumor.American journal of ophthalmology case reports · 2025Article
- Heterozygous Germline Fanconi Anemia-Related Gene Mutations Increase Susceptibility to Germ Cell Tumors.JCO precision oncology · 2025Article
- Article
- Global, regional, and national burden of genitourinary cancers in 204 countries and territories, 1990-2021: a systematic analysis for the global burden of disease study 2021.Journal of the National Cancer Center · 2025Article
- Intravascular Germ Cell Tumor With Cardiac and Bilateral Pulmonary Artery Involvement.JACC. Case reports · 2025Article
- A Case of Primary Extragonadal Germ Cell Malignancy With Testicular Microlithiasis: Its Association and Significance.Cureus · 2025Article
- Adenocarcinoma With Intestinal and Pancreatobiliary Features Arising From a Sacrococcygeal Teratoma in an Adult Female: A Case Report.Case reports in pathology · 2025Article
- A rare case of huge intracranial yolk sac tumor presenting as an orbital mass in an infant: case report and literature review.Discover oncology · 2024Article
- Comparative analysis of testicular and nontesticular choriocarcinoma: a population-based study.Annals of medicine and surgery (2012) · 2024Article
- Maediastinal germ cell tumors: analysis using hospital-based cancer registry data in Japan.International journal of clinical oncology · 2024Article
- Extensive surgical resections for rare pleural neoplasms: a single-center experience with a yolk sac tumor and synovial sarcoma.World journal of surgical oncology · 2024Article
- Spontaneous rupture‑induced life‑threatening mediastinal mixed germ cell tumor: A case report and therapeutic considerations.Oncology letters · 2024Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Germ cell tumours (GCTs) most often arise in the gonads, but some develop extragonadally. The aim of this study was to examine gender- and race-specific trends in incidence and survival of gonadal (GGCTs) and extragonadal GCTs (EGCTs) in the US from 1973 to 2007. We also examined the topographical distribution of EGCTs by race and gender. We estimated age-specific and age-standardized incidence rates and 5-year relative survival rates (RSR) of GCTs using the Surveillance, Epidemiology and End Results (SEER) Program (SEER nine registries). GCTs and their topographical sites were identified using ICD-O morphology and topography codes. Of 21,170 GCTs among males, 5.7% were extragonadal (Whites 5.5%; Blacks 16.3%). Of 2093 GCTs among females, 39.3% were extragonadal (Whites, 36.9%; Blacks 51.0%). The incidence of GGCT was much higher among White (56.3/1,000,000) than Black males (10.0/1,000,000), while there was no difference in incidence between White and Black females (3.2/1,000,000). The rates of EGCT among men and women of both races were similar (range:1.9-3.4/1,000,000). The most frequent extragonadal sites were mediastinum among males and placenta among females. The 5-year RSR of testicular GCT was higher among Whites (97%) than Blacks (90%), as was the 5-year RSR of ovarian GCT (Whites, 92%; Blacks 85%). In general, the 5-year RSRs of EGCTs were lower than the 5-year RSRs of GGCTs. The different incidence trends of GGCTs and EGCTs and distinct age-specific incidence patterns by anatomical site of EGCTs suggest that GGCTs and EGCTs may have different aetiologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.