Evidence map›Paper›PMID 22319527›Full record

ArticleInternational journal of endocrinology2012

Male fertility and reduction in semen parameters: a single tertiary-care center experience.

D Milardi, G Grande, D Sacchini, A L Astorri, G Pompa, A Giampietro, L De Marinis, A Pontecorvi, A G Spagnolo, R Marana

Open access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Semen Characteristics and Embryo Outcomes in IVF.Journal of family & reproductive health · 2025
    Article
  4. Article
  5. Article
  6. Human Infertility and Reproductive Endocrinology.Life (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Effects of a short abstinence period on sperm quality in oligozoospermic men.Clinical and experimental reproductive medicine · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

D MilardiDepartment of Obstetrics and Gynecology, International Scientific Institute "Paolo VI", Catholic University of the Sacred Heart, Largo A. Gemelli 8, 00168 Rome, Italy.
G Grande
D Sacchini
A L Astorri
G Pompa
A Giampietro
L De Marinis
A Pontecorvi
A G Spagnolo
R Marana
Università Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. Infertility is both a clinical and a public problem, affecting the life of the couple, the healthcare services, and social environment. Standard semen analysis is the surrogate measure of male fertility in clinical practice. Objective. To provide information about the relationship between semen parameters and spontaneous conception. Methods. We evaluated retrospectively 453 pregnancies that occurred among 2935 infertile couples evaluated at an infertility clinic of a tertiary-care university hospital, between 2004 and 2009. Results. Normal semen analysis was present only in 158 patients; 295 subfertile patients showed alterations in at least one seminal parameter. A reduction in all seminal parameters was observed in 41 patients. Etiological causes of male infertility were identified in 314 patients. Conclusion. Our data highlights the possibility of a spontaneous conception with semen parameters below WHO reference values. Therefore, we support the importance of defining reference values on a population of fertile men. Finally, we analyzed the related ethical issues.

Identifiers

PMID22319527
PMCPMC3272805
OpenAlexW2046058882

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.