ArticleInterdisciplinary toxicology2011
Toxicological aspects of the use of phenolic compounds in disease prevention.
Article in Interdisciplinary toxicology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 122 citations in OpenAlex.
- Toxic Plants Potentially Impacting the Health Status of Livestock in St. Kitts-A Surveillance Study.Toxins · 2026Article
- Regulatory Mechanisms of Phenolic Acids in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review.Antioxidants (Basel, Switzerland) · 2025Review
- Antiviral Activity of Brazilian Propolis from Stingless Bees Against Rotavirus.Microorganisms · 2025Article
- Targeting the Parkinson's disease using sim (Rhodomyrtus tomentosa) fruit water extract.BMC complementary medicine and therapies · 2025Article
- Fabrication of Luminescent Microtiterplate Using Terbium Complex for Phenol Screening in Seawater Samples.Journal of fluorescence · 2025Article
- Wound healing potential and anti-inflammatory action of extracts and compounds of Myrciaria plinioides D. Legrand leaves.Inflammopharmacology · 2024Article
- Antitumor Effects and the Potential Mechanism of 10-HDA against SU-DHL-2 Cells.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Marine Polyphenols in Cardiovascular Health: Unraveling Structure-Activity Relationships, Mechanisms, and Therapeutic Implications.International journal of molecular sciences · 2024Review
- Review
- Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic diseases.Frontiers in immunology · 2024Review
- Modulation of Caco-2 Colon Cancer Cell Viability and CYP2W1 Gene Expression by Hesperidin-treatedAnti-cancer agents in medicinal chemistry · 2024Article
- Oleuropein Stimulates Migration of Human Trophoblast Cells and Expression of Invasion-Associated Markers.International journal of molecular sciences · 2023Article
- Ethanolic Extract Propolis-Loaded Niosomes Diminish Phospholipase B1, Biofilm Formation, and Intracellular Replication ofMolecules (Basel, Switzerland) · 2023Article
- Teratogen Potential Evaluation of the Aqueous and Hydroalcoholic Leaf Extracts ofPlants (Basel, Switzerland) · 2023Article
- Toxicity and Anti-Inflammatory Activity of Phenolic-Rich Extract fromPlants (Basel, Switzerland) · 2023Article
- Effect of Raw and Roasted Phoenix dactylifera L. Seed Polyphenols Extracts on Suppression of Angiogenesis in Endothelial Cells.Plant foods for human nutrition (Dordrecht, Netherlands) · 2022Article
- Exercise Training andPlants (Basel, Switzerland) · 2022Article
- Effects of Functional Phenolics Dietary Supplementation on Athletes' Performance and Recovery: A Review.International journal of molecular sciences · 2022Review
- Automatic Identification of Myeloperoxidase Natural Inhibitors in Plant Extracts.Molecules (Basel, Switzerland) · 2022Article
- Phenolics as GABAMolecules (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The consumption of a diet low in fat and enhanced by fruits and vegetables, especially rich in phenolic compounds, may reduce risks of many civilization diseases. The use of traditional medicines, mainly derived from plant sources, has become an attractive segment in the management of many lifestyle diseases. Concerning the application of dietary supplements (based on phenolic compounds) in common practice, the ongoing debate over possible adverse effects of certain nutrients and dosage levels is of great importance. Since dietary supplements are not classified as drugs, their potential toxicities and interactions have not been thoroughly evaluated. First, this review will introduce phenolic compounds as natural substances beneficial for human health. Second, the potential dual mode of action of flavonoids will be outlined. Third, potential deleterious impacts of phenolic compounds utilization will be discussed: pro-oxidant and estrogenic activities, cancerogenic potential, cytotoxic effects, apoptosis induction and flavonoid-drug interaction. Finally, future trends within the research field will be indicated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.