ArticleStroke research and treatment2012
Small vessel cerebrovascular disease: the past, present, and future.
Article in Stroke research and treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Association between stress hyperglycaemia ratio and admission stroke severity: a retrospective study in a Chinese single-centre cohort.BMJ open · 2025Article
- Spiral time-of-flight magnetic resonance angiography for intracranial vascular imaging: performance compared to conventional Cartesian angiogram.Quantitative imaging in medicine and surgery · 2024Article
- Article
- Long-term mortality and recurrent vascular events in lacunar versus non-lacunar ischaemic stroke: A cohort study.European stroke journal · 2022Article
- Optical measures of cerebral arterial stiffness are associated with white matter signal abnormalities and cognitive performance in normal aging.Neurobiology of aging · 2019Article
- Synergistic Anti-Angiogenic Effects Using Peptide-Based Combinatorial Delivery of siRNAs Targeting VEGFA, VEGFR1, and Endoglin Genes.Pharmaceutics · 2019Article
- Twenty-and-a-half syndrome: a case report.Journal of medical case reports · 2019Article
- Improvement of postoperative cognitive dysfunction and attention network function of patients with ischemic cerebrovascular disease via dexmedetomidine.Experimental and therapeutic medicine · 2018Article
- Retinal microvascular network alterations: potential biomarkers of cerebrovascular and neural diseases.American journal of physiology. Heart and circulatory physiology · 2017Review
- [Frequency and characteristics of strokes involving the perforating arteries in the Department of Neurology at the Befelatanana General Hospital, Antananarivo].The Pan African medical journal · 2017Article
- In Vitro Study of a Superhydrophilic Thin Film Nitinol Endograft that is Electrostatically Endothelialized in the Catheter Prior to the Endovascular Procedure.Journal of functional biomaterials · 2016Article
- Beyond antiplatelets: The role of glycoprotein VI in ischemic stroke.International journal of stroke : official journal of the International Stroke Society · 2016Review
- Stroke subtypes and factors associated with ischemic stroke in Kinshasa, Central Africa.African health sciences · 2015Article
- Outdoor air pollution, subtypes and severity of ischemic stroke--a small-area level ecological study.International journal of health geographics · 2014Article
- Do eye movement impairments in patients with small vessel cerebrovascular disease depend on lesion load or on cognitive deficits? A video-oculographic and MRI study.Journal of neurology · 2014Article
- Ultrasound-enhanced protective effect of tetramethylpyrazine against cerebral ischemia/reperfusion injury.PloS one · 2014Article
- Angiotensin-converting enzyme gene insertion/deletion polymorphism and small vessel cerebral stroke in Indian population.International journal of vascular medicine · 2014Article
- Small vessel disease and memory loss: what the clinician needs to know to preserve patients' brain health.Current cardiology reports · 2013Review
- Significance of Haemodynamic and Haemostatic Factors in the Course of Different Manifestations of Cerebral Small Vessel Disease: The SHEF-CSVD Study-Study Rationale and Protocol.Neuroscience journal · 2013Article
- The vascular neural network--a new paradigm in stroke pathophysiology.Nature reviews. Neurology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain infarction due to small vessel cerebrovascular disease (SVCD)-also known as small vessel infarct (SVI) or "lacunar" stroke-accounts for 20% to 25% of all ischemic strokes. Historically, SVIs have been associated with a favorable short-term prognosis. However, studies over the years have demonstrated that SVCD/SVI is perhaps a more complex and less benign phenomenon than generally presumed. The currently employed diagnostic and therapeutic strategies are based upon historical and contemporary perceptions of SVCD/SVI. What is discovered in the future will unmask the true countenance of SVCD/SVI and help furnish more accurate prognostication schemes and effective treatments for this condition. This paper is an overview of SVCD/SVI with respect to the discoveries of the past, what is known now, and what will the ongoing investigations evince in the future.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.