Evidence map›Paper›PMID 22315617›Full record

ArticleStem cells international2012

Mesenchymal stem cells and cardiovascular disease: a bench to bedside roadmap.

Manuel Mazo, Miriam Araña, Beatriz Pelacho, Felipe Prosper

Abstract read
In one paragraph

Article in Stem cells international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Functions of Mesenchymal Stem Cells in Cardiac Repair.Advances in experimental medicine and biology · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Cardiac Regenerative Medicine: The Potential of a New Generation of Stem Cells.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2016
    Review
  10. Article
  11. Article
  12. From bench to bedside: use of human adipose-derived stem cells.Stem cells and cloning : advances and applications · 2015
    Review
  13. Article
  14. Article
  15. Stem cell therapy for chronic heart failure: an updated appraisal.Expert opinion on biological therapy · 2013
    Review
  16. Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manuel MazoDepartment of Hematology and Cell Therapy, Clínica Universidad de Navarra, Foundation for Applied Medical Research, University of Navarra, Avenida Pío XII 36, Pamplona, 31008 Navarra, Spain.
Miriam Araña
Beatriz Pelacho
Felipe Prosper

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the incredible boost in stem cell research has kindled the expectations of both patients and physicians. Mesenchymal progenitors, owing to their availability, ease of manipulation, and therapeutic potential, have become one of the most attractive options for the treatment of a wide range of diseases, from cartilage defects to cardiac disorders. Moreover, their immunomodulatory capacity has opened up their allogenic use, consequently broadening the possibilities for their application. In this review, we will focus on their use in the therapy of myocardial infarction, looking at their characteristics, in vitro and in vivo mechanisms of action, as well as clinical trials.

Identifiers

PMID22315617
PMCPMC3270473

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.