Evidence map›Paper›PMID 22315131›Full record

ArticleBreast cancer research and treatment2012

Willingness to use tamoxifen to prevent breast cancer among diverse women.

Celia Patricia Kaplan, Sue E Kim, Sabrina T Wong, George F Sawaya, Judith M E Walsh, Eliseo J Pérez-Stable

Abstract read
In one paragraph

Article in Breast cancer research and treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Trial
  3. A randomized, controlled trial to increase discussion of breast cancer in primary care.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Tamoxifen for women at high risk of breast cancer.Breast cancer (Dove Medical Press) · 2014
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Celia Patricia KaplanDivision of General Internal Medicine, Department of Medicine, University of California San Francisco, 3333 California Street, San Francisco, CA 94143-0856, USA.
Sue E Kim
Sabrina T Wong
George F Sawaya
Judith M E Walsh
Eliseo J Pérez-Stable
University of California, San Francisco · USManpower Demonstration Research Corporation · USUCSF Helen Diller Family Comprehensive Cancer Center · USUniversity of British Columbia · CAUniversity of San Francisco · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
RESOURCE CENTER FOR AGING RESEARCH IN DIVERSE POPULATIONP30AG015272 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEAH S KARLINER · 1997 to 2026
$19.5M
Race/ethnicity and trust in the doctor-patient relationshipP01HS010856 · AHRQ · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI WASHINGTON, A EUGENE · 2000 to 2004
–
AHRQ HHS 5P01 HS10856)AHRQ HHS P01 HS010856NCRR NIH HHS UL1 RR024131NIA NIH HHS P30 AG015272NIA NIH HHS P30-AG15272
6 · The paper itself

Abstract

Use of chemoprevention to prevent development of breast cancer among high-risk women has been limited despite clinical evidence of its benefit. Our goals were to determine whether knowledge of the benefits and risks of tamoxifen affects a woman's willingness to take it to prevent breast cancer, to define factors associated with willingness to take tamoxifen, and to evaluate race/ethnic differences. Women, ages 50-80, who identified as African American, Asian, Latina, or White, and who had at least one visit to a primary care physician in the previous 2 years, were recruited from ambulatory practices. After a screening telephone survey, women completed an in-person interview in their preferred language. Multivariate regression models were constructed to examine the associations of demographic characteristics, numeracy, breast cancer history, and health knowledge with willingness to take tamoxifen. Over 40% of the women reported they would likely take tamoxifen if determined to be at high risk, and 31% would be somewhat likely to do so. Asian women, those with no insurance, and those with less than high school education were significantly more likely to be willing to take tamoxifen. Higher scores on numeracy and on breast cancer knowledge were also associated with willingness to take tamoxifen. A higher tamoxifen knowledge score was inversely related to willingness to take the drug. Factors affecting women's willingness to take breast cancer chemoprevention drugs vary and are not determined solely by knowledge of risk/benefit or risk perception.

Indexed as

AgedAnticarcinogenic AgentsAsianBlack or African AmericanBreast NeoplasmsEducational StatusFemaleHealth Knowledge, Attitudes, PracticeHispanic or LatinoHumansMiddle AgedMultivariate AnalysisPatient Acceptance of Health CareRegression AnalysisRisk FactorsTamoxifenAnticarcinogenic AgentsTamoxifen

Identifiers

PMID22315131
PMCPMC4039196
OpenAlexW2051557651

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.