ReviewCurrent neurology and neuroscience reports2012
The management of sleep and circadian disturbance in patients with dementia.
Review in Current neurology and neuroscience reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Trial
- The Relationship between Circadian Rhythm and Cancer Disease.International journal of molecular sciences · 2024Review
- Pilot Study of the Effects of Bright Ambient Therapy on Dementia Symptoms and Cognitive Function.Frontiers in psychology · 2021Article
- Association between Daily Activities and Behavioral and Psychological Symptoms of Dementia in Community-Dwelling Older Adults with Memory Complaints by Their Families.International journal of environmental research and public health · 2020Article
- Restrictive Ventilatory Patterns in Residents of Continuing Care Retirement Communities.Western journal of nursing research · 2019Article
- Best practice in the management of behavioural and psychological symptoms of dementia.Therapeutic advances in neurological disorders · 2017Review
- Rest-activity rhythms in small scale homelike care and traditional care for residents with dementia.BMC geriatrics · 2017Article
- Blue light therapy improves circadian dysfunction as well as motor symptoms in two mouse models of Huntington's disease.Neurobiology of sleep and circadian rhythms · 2017Article
- Current Concepts in the Diagnosis and Treatment of Sleep Disorders in the Elderly.Current psychiatry reports · 2015Article
- Effect of home-based light treatment on persons with dementia and their caregivers.Lighting research & technology (London, England : 2001) · 2015Article
- Addressing sleep disturbances: an opportunity to prevent cardiometabolic disease?International review of psychiatry (Abingdon, England) · 2014Review
- The Bedford Alzheimer nursing-severity scale to assess dementia severity in advanced dementia: a nonparametric item response analysis and a study of its psychometric characteristics.American journal of Alzheimer's disease and other dementias · 2014Article
- Circadian rhythm abnormalities.Continuum (Minneapolis, Minn.) · 2013Review
- Classification of sleep disorders.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2012Review
- Sleep in the Elderly.Missouri medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep and circadian disturbances are common among patients with dementia. Symptomatic manifestations vary according to dementia subtype, with one commonly shared pattern--the irregular sleep-wake rhythm (ISWR), a circadian disorder characterized by an absence of the sleepwake cycle’s circadian synchronization. Hypothesized mechanisms of circadian rhythm disturbance include suprachiasmatic nucleus (SCN) circadian pacemaker damage, pineal gland and melatonin secretion alterations, and reduced zeitbeigers and decreased input to the SCN. Management options include prescribed sleep/wake scheduling, light therapy, melatonin, physical and social activity, and mixed modality. The mixed-modality approach is the most effective method in treating ISWR. Pharmacologic interventions are controversial, with no evidence supporting their effectiveness while associated with multiple side effects. They should be used with caution and only be considered as short-term therapy. All treatment strategies should be individualized to achieve the best outcomes.
Indexed as
Identifiers
22314860What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.