ArticleBJOG : an international journal of obstetrics and gynaecology2012
The spontaneous resolution of heavy menstrual bleeding in the perimenopausal years.
Article in BJOG : an international journal of obstetrics and gynaecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06798584 (Rough Journey to Menopause), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Rough Journey to Menopause: How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?
Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Usual medical treatments or levonorgestrel-IUS for women with heavy menstrual bleeding: long-term randomised pragmatic trial in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016Trial
- The interplay of von Willebrand disease and women's reproductive health.Blood advances · 2026Review
- Heavy menstrual bleeding and association with menstruation-specific resources: A multinational cross-sectional study in low- and middle-income countries.Health & place · 2025Article
- Spatial, temporal and demographic distribution characteristics of adenomyosis symptom clusters from the perspective of traditional Chinese medicine: a multicenter cross-sectional study in China from 2020 to 2022.Frontiers in endocrinology · 2025Article
- The Effectiveness of Levonorgestrel-Releasing Intrauterine System in the Treatment of Heavy Menstrual Bleeding.Journal of obstetrics and gynaecology of India · 2016Article
- Management of endometrial modifications in perimenopausal women.Clujul medical (1957) · 2015Review
- The relation of heavy or prolonged bleeding during the menopause transition to risk of hysterectomy.Women's health (London, England)Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo obtain estimates of the rate of spontaneous resolution of heavy menstrual bleeding and to explore any association with specific menstrual symptoms.
designTwo-year prospective cohort study.
settingSeven general practices, with 67 100 registered patients. POPULATION: All women aged 40-54 years on the practices age-sex registers.
methodsBaseline postal questionnaire, with follow-up questionnaires sent to naturally menstruating respondents at 6, 12, 18 and 24 months.
main outcome measuresRate of spontaneous resolution of heavy menstrual bleeding in naturally menstruating women.
resultsA total of 7121 baseline questionnaires were sent out, with an initial response rate of 63%. We recruited 2051 naturally menstruating women for the prospective cohort study. The spontaneous rate of resolution of heavy menstrual bleeding varied from 8.1% (95% CI 5.3-12%) in women aged 45-49 years, who had resolution without recurrence for 24 months, to 35% (95% CI 30-41%) in women aged 50-54 years, who had resolution without recurrence for 6 months. Rates were lower in those who reported interference with life from heavy menstrual bleeding. There was a strong association between the spontaneous resolution of heavy menstrual bleeding and skipped periods in women aged over 45 years. The association with 'cycle too variable to say' was significant, but weaker.
conclusionThere is a high prevalence, incidence and significant spontaneous rate of resolution of heavy menstrual bleeding in naturally menstruating women during the perimenopausal years. The rates have potential use for individual women, clinical decisions, devising and implementing interventions and planning the care of populations.
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