Evidence map›Paper›PMID 22312588›Full record

ArticleBiomedical optics express2012

Label-free imaging of zebrafish larvae in vivo by photoacoustic microscopy.

Shuoqi Ye, Ran Yang, Jingwei Xiong, K Kirk Shung, Qifa Zhou, Changhui Li, Qiushi Ren

Abstract read
In one paragraph

Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. A Novel Fisheye-Lens-Based Photoacoustic System.Sensors (Basel, Switzerland) · 2016
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Photoacoustic Microscopy.Laser & photonics reviews · 2013
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuoqi Ye
Ran Yang
Jingwei Xiong
K Kirk Shung
Qifa Zhou
Changhui Li
Qiushi Ren

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zebrafish play an important role in biological and biomedical research. Traditional in vivo imaging methods for studying zebrafish larvae primarily require fluorescence labeling. In this work, relying on tissue intrinsic optical absorption contrast, we acquired high resolution label-free 3D images of zebrafish larvae by using photoacoustic microscopy (PAM) in vivo. The spatial resolution reaches several microns, allowing the study of microstructures in various living organs. We demonstrated that our method has the potential to be a powerful non-invasive imaging method for studying various small animal models, including zebrafish larvae, Caenorhabditis elegans, frogs and drosophila larvae.

Indexed as

(170.3880) Medical and biological imaging(170.5120) Photoacoustic imaging(170.6900) Three-dimensional microscopy

Identifiers

PMID22312588
PMCPMC3269852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.