Evidence map›Paper›PMID 22312308›Full record

ReviewInternational journal of molecular sciences2012

Clinical significance of serum biomarkers in pediatric solid mediastinal and abdominal tumors.

John A Sandoval, Linda H Malkas, Robert J Hickey

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Review
  3. Mediastinal tumors: why, when, and how to biopsy?Mediastinum (Hong Kong, China) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Review
  13. Article
  14. Relevance of miR-21 in HIV and non-HIV-related lymphomas.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

John A SandovalDepartment of Surgery, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS332, Room D3040G, Memphis, TN 38105, USA.
Linda H MalkasCity of Hope Cancer Center, Duarte, CA 91010, USA.
Robert J HickeyCity of Hope Cancer Center, Duarte, CA 91010, USA.
St. Jude Children's Research Hospital · USCity of Hope · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accurate detection of these malignancies. This review summarizes available solid tumor serum biomarkers with a special focus on mediastinal and abdominal cancers in children.

Indexed as

alpha-FetoproteinsBiomarkers, TumorCA-125 AntigenCatecholaminesChildEnzymesHumansMediastinal NeoplasmsMembrane GlycoproteinsNeoplasmsPeptide Hormonesalpha-FetoproteinsBiomarkers, TumorCA-125 AntigenCatecholaminesEnzymesMembrane GlycoproteinsPeptide Hormonesabdominal massmediastinal masspediatric solid tumorsserum biomarkers

Identifiers

PMID22312308
PMCPMC3269742
OpenAlexW2058403895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.