ReviewInternational journal of molecular sciences2012
Nanostructured biomaterials for tissue engineered bone tissue reconstruction.
Review in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- 3D printing combined with thermally induced phase separation for engineering hierarchical osteogenic PLA scaffolds.Materials today. Bio · 2025Article
- Polymeric Composite Thin Films Deposited by Laser Techniques for Antimicrobial Applications-A Short Overview.Polymers · 2025Review
- Prediction of Bone Formation Rate of Artificial Bone With Machine Learning Models Considering the Variation of Experimental Results.Analytical science advances · 2025Article
- Biobased Nanomaterials: Pioneering Innovations for Biomedical Advancements.Pharmaceutical nanotechnology · 2025Review
- Evaluation of Physiochemical and Biological Properties of Biofunctionalized Mg-Based Implants Obtained via Large-Scale PEO Process for Dentistry Applications.Journal of functional biomaterials · 2023Article
- Recent Advancements in Electrospun Chitin and Chitosan Nanofibers for Bone Tissue Engineering Applications.Journal of functional biomaterials · 2023Review
- Multifunctional Scaffolds Based on Emulsion and Coaxial Electrospinning Incorporation of Hydroxyapatite for Bone Tissue Regeneration.International journal of molecular sciences · 2022Review
- Osteogenic enhancement of modular ceramic nanocomposites impregnated with human dental pulp stem cells: an approach for bone repair and regenerative medicine.Journal, genetic engineering & biotechnology · 2022Article
- Research progress, models and simulation of electrospinning technology: a review.Journal of materials science · 2022Review
- Osteogenic and antibacterial dual functions of a novel levofloxacin loaded mesoporous silica microspheres/nano-hydroxyapatite/polyurethane composite scaffold.Genes & diseases · 2021Article
- Nanostructured Biomaterials forCurrent opinion in biomedical engineering · 2021Article
- Comprehensive Survey on Nanobiomaterials for Bone Tissue Engineering Applications.Nanomaterials (Basel, Switzerland) · 2020Review
- From Dermal Patch to Implants-Applications of Biocomposites in Living Tissues.Molecules (Basel, Switzerland) · 2020Review
- Review
- Natural Polymeric Scaffolds in Bone Regeneration.Frontiers in bioengineering and biotechnology · 2020Review
- Randomized Controlled Clinical Trial of Nanostructured Carbonated Hydroxyapatite for Alveolar Bone Repair.Materials (Basel, Switzerland) · 2019Article
- Electrospun polycaprolactone/hydroxyapatite/ZnO nanofibers as potential biomaterials for bone tissue regeneration.Journal of materials science. Materials in medicine · 2019Article
- A Multicentre Study: The Use of Micrografts in the Reconstruction of Full-Thickness Posttraumatic Skin Defects of the Limbs-A Whole Innovative Concept in Regenerative Surgery.Stem cells international · 2019Article
- Novel potential scaffold for periodontal tissue engineering.Clinical oral investigations · 2017Article
- RETRACTED: Porcine Bone Scaffolds Adsorb Growth Factors Secreted by MSCs and Improve Bone Tissue Repair.Materials (Basel, Switzerland) · 2017Article
Corrections and comments
- Erratum issuedChiara, Gardin [corrected to Gardin, Chiara]; Letizia, Ferroni [corrected to Ferroni, Letizia]; Lorenzo, Favero [corrected to Favero, Lorenzo]; Edoardo, Stellini [corrected to Stellini, Edoardo]; Diego, Stomaci [corrected to Stomaci, Diego]; Stefano, Sivol
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone tissue engineering strategies are emerging as attractive alternatives to autografts and allografts in bone tissue reconstruction, in particular thanks to their association with nanotechnologies. Nanostructured biomaterials, indeed, mimic the extracellular matrix (ECM) of the natural bone, creating an artificial microenvironment that promotes cell adhesion, proliferation and differentiation. At the same time, the possibility to easily isolate mesenchymal stem cells (MSCs) from different adult tissues together with their multi-lineage differentiation potential makes them an interesting tool in the field of bone tissue engineering. This review gives an overview of the most promising nanostructured biomaterials, used alone or in combination with MSCs, which could in future be employed as bone substitutes. Recent works indicate that composite scaffolds made of ceramics/metals or ceramics/polymers are undoubtedly more effective than the single counterparts in terms of osteoconductivity, osteogenicity and osteoinductivity. A better understanding of the interactions between MSCs and nanostructured biomaterials will surely contribute to the progress of bone tissue engineering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.