Trial reportPediatrics2012
Resilience in children undergoing stem cell transplantation: results of a complementary intervention trial.
Trial report in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Pooled it
- Effects of the application of therapeutic massage in children with cancer: a systematic review.Revista latino-americana de enfermagem · 2017Pooled it
- Psychological therapies for children and adolescents exposed to trauma.The Cochrane database of systematic reviews · 2016Pooled it
- Yoga in addition to standard care for patients with haematological malignancies.The Cochrane database of systematic reviews · 2014Pooled it
- Effects of laughter therapy on quality of life in patients with cancer: An open-label, randomized controlled trial.PloS one · 2019Trial
- Group-Based Trajectory Modeling of Distress and Well-Being Among Caregivers of Children Undergoing Hematopoetic Stem Cell Transplant.Journal of pediatric psychology · 2017Trial
- Adjustment in parents of children undergoing stem cell transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014Trial
- Trial
- The Mechanism by 18 RCTs Psychosocial Interventions Affect the Personality, Emotions, and Behaviours of Paediatric and Young Adult Cancer Patients: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Patient-reported outcome measures in children, adolescents, and young adults with palliative care needs-a scoping review.BMC palliative care · 2023Article
- Early Interventions to Prevent Post-Traumatic Stress Disorder in Youth after Exposure to a Potentially Traumatic Event: A Scoping Review.Healthcare (Basel, Switzerland) · 2022Article
- The Power of Massage in Children with Cancer-How Can We Do Effective Research?Children (Basel, Switzerland) · 2019Review
- Caregiver Perceptions of Music Therapy for Children Hospitalized for a Blood and Marrow Transplant: An Interpretivist Investigation.Global advances in health and medicine · 2018Article
- The Impact of Cancer and its Treatment on the Growth and Development of the Pediatric Patient.Current pediatric reviews · 2017Review
- Epidemiology of complementary and alternative medicine therapy use in allogeneic hematopoietic stem cell transplant survivorship patients in Australia.Cancer medicine · 2016Article
- Integrative Therapy Use for Management of Side Effects and Toxicities Experienced by Pediatric Oncology Patients.Children (Basel, Switzerland) · 2014Review
- Posttraumatic stress and psychological growth in children with cancer: has the traumatic impact of cancer been overestimated?Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Article
- The neural basis of humour processing.Nature reviews. Neuroscience · 2013Review
- Translational reciprocity: bridging the gap between preclinical studies and clinical treatment of stress effects on the adolescent brain.Neuroscience · 2013Review
- Can mindfulness-based interventions help adolescents with cancer?Psycho-oncology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundChildren undergoing stem cell transplantation (SCT) are thought to be at risk for increased distress, adjustment difficulties, and impaired health-related quality of life (HRQL). We report results of a multisite trial designed to improve psychological adjustment and HRQL in children undergoing SCT.
methodsA total of 171 patients and parents from 4 sites were randomized to receive a child-targeted intervention; a child and parent intervention; or standard care. The child intervention included massage and humor therapy; the parent intervention included massage and relaxation/imagery. Outcomes included symptoms of depression and posttraumatic stress, HRQL, and benefit finding. Assessments were conducted by patient and parent report at admission and SCT week+24.
resultsAcross the sample, significant improvements were seen on all outcomes from admission to week+24. Surprisingly, patients who had SCT reported low levels of adjustment difficulties at admission, and improved to normative or better than average levels of adjustment and HRQL at week+24. Benefit finding was high at admission and increased at week+24; however, there were no statistically significant differences between intervention arms for any of the measures.
conclusionsAlthough the results do not support the benefits of these complementary interventions in pediatric SCT, this may be explained by the remarkably positive overall adjustment seen in this sample. Improvements in supportive care, and a tendency for patients to find benefit in the SCT experience, serve to promote positive outcomes in children undergoing this procedure, who appear particularly resilient to the challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.