Evidence map›Paper›PMID 22311967›Full record

ReviewPhysiology (Bethesda, Md.)2012

New insights into molecular players involved in neurotransmitter release.

Pablo Ariel, Timothy A Ryan

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. SNARE Proteins in Synaptic Vesicle Fusion.Advances in neurobiology · 2023
    Article
  3. Endogenous Tagging Reveals Differential Regulation of CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
  10. Myosin II regulates activity dependent compensatory endocytosis at central synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pablo ArielDepartment of Biochemistry, Weill Cornell Medical College, New York, New York, USA
Timothy A Ryan

Funding

Physiology of Single Synaptic CNS TerminalsR01NS036942 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Timothy Aidan Ryan · 1998 to 2026
$6.8M
Quantitative Mapping of Molecules and Release Properties at Nerve TerminalsR01MH085783 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI RYAN, TIMOTHY AIDAN · 2010 to 2019
$4.4M
Physiology of Single Synaptic CNS TerminalsR37NS036942 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI RYAN, TIMOTHY AIDAN · 2016 to 2022
$3.5M
NIMH NIH HHS MH-085783NIMH NIH HHS R01 MH085783NINDS NIH HHS NS-036942NINDS NIH HHS R01 NS036942NINDS NIH HHS R37 NS036942
6 · The paper itself

Abstract

The strength of a synapse can profoundly influence network function. How this strength is set at the molecular level is a key question in neuroscience. Here, we review a simple model of neurotransmission that serves as a convenient framework to discuss recent studies on RIM and synaptotagmin.

Indexed as

Models, NeurologicalAnimalsATP-Binding Cassette TransportersNeurotransmitter AgentsSynapsesSynaptic TransmissionSynaptotagminsATP-Binding Cassette TransportersNeurotransmitter AgentsSynaptotagmins

Identifiers

PMID22311967
PMCPMC3703655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.