Evidence map›Paper›PMID 22311563›Full record

ReviewJournal of cardiovascular translational research2012

Electrical and mechanical ventricular activation during left bundle branch block and resynchronization.

Marc Strik, François Regoli, Angelo Auricchio, Frits Prinzen

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Journal of cardiovascular translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04328649 (Clinical, Structural and Mechanical Features in Patients With Left Bundle Branch Block), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04328649 unknown statusnot on this mapstarted 2020, after this paper: background citation

Clinical, Structural and Mechanical Features in Patients With Left Bundle Branch Block: an Observational and Prospective Study.

Typeobservational_patient_registrySponsorPoliclinico Casilino ASL RMBRan2020 to 2025Enrolled250ConditionsLeft Bundle-Branch Block, Electrocardiographic Pattens, Clinical Features
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Association between left ventricular lead position and intrinsic QRS morphology with regard to clinical outcome in cardiac resynchronization therapy for heart failure.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Article
  9. Article
  10. Article
  11. Association of ECG characteristics with clinical and echocardiographic outcome to CRT in a non-LBBB patient population.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Left Univentricular Pacing by Rate-Adaptive Atrioventricular Delay in Treatment of Chronic Heart Failure.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Optimal Strategies on Avoiding CRT Nonresponse.Current treatment options in cardiovascular medicine · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marc StrikDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht 6200 MD, The Netherlands. m.strik@maastrichtuniversity.nl
François Regoli
Angelo Auricchio
Frits Prinzen
Epatocentro Ticino · CHMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac resynchronization therapy (CRT) aims to treat selected heart failure patients suffering from conduction abnormalities with left bundle branch block (LBBB) as the culprit disease. LBBB remained largely underinvestigated until it became apparent that the amount of response to CRT was heterogeneous and that the therapy and underlying pathology were thus incompletely understood. In this review, current knowledge concerning activation in LBBB and during biventricular pacing will be explored and applied to current CRT practice, highlighting novel ways to better measure and treat the electrical substrate.

Indexed as

Cardiac Resynchronization TherapyBundle-Branch BlockElectrocardiographyHumansTreatment OutcomeVentricular Function, Left

Identifiers

PMID22311563
PMCPMC3294208
OpenAlexW2086924764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.