Evidence map›Paper›PMID 22311102›Full record

ReviewLangenbeck's archives of surgery2012

A critical appraisal of the hemodynamic signal driving liver regeneration.

Kerstin Abshagen, Christian Eipel, Brigitte Vollmar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Langenbeck's archives of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Hepatic Arterioportal Fistula Is Associated with Decreased Future Liver Remnant Regeneration after Stage-I ALPPS for Hepatocellular Carcinoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  11. Article
  12. Review
  13. Liver Regeneration after Hepatectomy and Partial Liver Transplantation.International journal of molecular sciences · 2020
    Review
  14. Hemostasis and Liver Regeneration.Seminars in thrombosis and hemostasis · 2020
    Review
  15. Article
  16. The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019
    Article
  17. Review
  18. Article
  19. Article
  20. Update on the Mechanisms of Liver Regeneration.Seminars in liver disease · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kerstin AbshagenInstitute for Experimental Surgery, University of Rostock, 18055 Rostock, Germany. kerstin.abshagen@uni-rostock.de
Christian Eipel
Brigitte Vollmar

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany aspects of the signaling mechanisms involved in the initiation of hepatic regeneration are under current investigation. Nevertheless, the actual mechanisms switching liver regeneration on and off are still unknown. Hemodynamic changes in the liver following partial hepatectomy have been suggested to be a primary stimulus in triggering liver regeneration. Most of the new knowledge about the impact of hemodynamic changes on liver regeneration is both conceptually important and directly relevant to clinical problems. PURPOSE: The purpose of this review is therefore to exclusively address the hemodynamic signal driving the liver regeneration process.

Indexed as

AnimalsCell ProliferationDisease Models, AnimalEndothelium, VascularHemodynamicsHepatectomyHepatic ArteryHepatocytesHumansKupffer CellsLiverLiver RegenerationMicrocirculationPortal VeinSignal TransductionVasoconstriction

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.