SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2012
Pregnancy-related pelvic girdle pain and its relationship with relaxin levels during pregnancy: a systematic review.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04620993 (Investigation of the Effect of Biomechanical and Viscoelastic Properties of Plantar Fascia on Pelvic Girdle Pain in Pregnant Women), which is not on this map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Effect of Biomechanical and Viscoelastic Properties of Plantar Fascia on Pelvic Girdle Pain in Pregnant Women
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of lumbopelvic pain during pregnancy: A systematic review and meta-analysis of cross-sectional studies.Acta obstetricia et gynecologica Scandinavica · 2024Pooled it
- Is pregnancy related pelvic girdle pain associated with altered kinematic, kinetic and motor control of the pelvis? A systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2012Pooled it
- Trial
- Comparative efficacy of lumbar and pelvic support on pain, disability, and motor control in women with postpartum pelvic girdle pain: a three-armed randomized controlled trial.BMC musculoskeletal disorders · 2025Trial
- Effect of preoperative anxiety on acute post-spinal low back pain after cesarean delivery: a prospective cohort study.Journal of anesthesia · 2026Article
- Participants' and physiotherapists' views on the delivery of a randomised controlled feasibility trial investigating a bespoke dynamic elastomeric fabric orthosis for women with chronic pelvic girdle pain: a qualitative exploration.Pilot and feasibility studies · 2026Article
- Pregnant Pitches: Navigating Football Before and During Pregnancy.Sports medicine (Auckland, N.Z.) · 2026Review
- Association Between the Duration of the Second Stage of Labor and Postpartum Lateral Pelvic Tilt in Women with Singleton Cephalic Vaginal Delivery.International journal of women's health · 2026Article
- Comparative Effectiveness of Nonpharmacological Therapies for Pregnancy-Related Low Back and Pelvic Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Orthopedic reviews · 2026Article
- Spinopelvic alignment and pubic symphysis widening are associated with postpartum low back pain: a retrospective case-control study.Frontiers in bioengineering and biotechnology · 2026Article
- Differential Diagnosis of Posterior Buttock Pain: A Conceptual Review Based on Topographic Localization of Pain, Is It Really the Sacroiliac Joint?International journal of spine surgery · 2025Article
- Navigating vaginal delivery in a patient with severe uterine prolapse: A case report.Case reports in women's health · 2025Article
- Global burden of low back pain from 1990 to 2021: a comprehensive analysis of risk factors and trends using the Global Burden of Disease Study 2021.BMC public health · 2025Article
- Assessment of the Association Between Neuraxial Anesthesia and Back Pain After Delivery: A Systematic Review and Meta-Analysis.Anesthesiology research and practice · 2025Article
- Pain Management for Postpartum Pain: A Narrative Review.Journal of pain research · 2025Review
- Biomechanical assessment of upright birthing positions using marker-based and markerless motion capture systems.PloS one · 2025Article
- Targeted Motor Control Considering Sternal Position Improves Spinal Alignment in Pregnant Women at Risk for Preterm Birth with Low Back Pain.Journal of clinical medicine · 2024Article
- A causal examination of the correlation between hormonal and reproductive factors and low back pain.Frontiers in endocrinology · 2024Article
- Generalized joint hypermobility and the risk of pregnancy-related pelvic girdle pain: Is body mass index of importance?-A prospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2023Article
- The Impact of Pelvic Osteotomies on Birth Canal Anatomy and Cesarean Section Rates: A Systematic Review.Journal of the Pediatric Orthopaedic Society of North America · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present systematic review assessed the level of evidence for the association between relaxin levels and pregnancy-related pelvic girdle pain (PPGP) during pregnancy.
methodsPRISMA guidelines were followed to conduct this systematic review. Electronic search was carried out using six different databases. Observational cohorts, cross-sectional or case-control studies focused on the association between relaxin levels and PPGP during pregnancy were included. Studies selection was conducted by two reviewers who screened firstly for titles, then for abstracts and finally for full articles. Risk of bias was assessed using the Newcastle-Ottawa scale and the quality of evidence by the guidelines proposed by the Cochrane back review group.
results731 references were identified. Six articles met the inclusion criteria and were considered for this systematic review. The main reason for the studies exclusion was PPGP related to gynaecological reasons. Five studies were case-control and one study was a prospective cohort. Four studies were ranked as high while two were ranked as low quality. Among the high quality studies, three found no association between PPGP and relaxin levels.
conclusionsBased on these findings, the level of evidence for the association between PPGP and relaxin levels was found to be low. PPGP assessment and controlling for risk factors were found to increase bias leaving uncertainty in interpretation of these findings and a need for further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.