ArticleThe Journal of heredity
Genetic mapping a meiotic driver that causes sex ratio distortion in the mosquito Aedes aegypti.
Article in The Journal of heredity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Genetic Dissection and Validation of Chromosomal Regions for Transmission Ratio Distortion in Intersubspecific Crosses of Rice.Frontiers in plant science · 2020Article
- Genome-Wide Transcriptome Profiling Reveals Genes Associated with Meiotic Drive System ofInsects · 2019Article
- Identification and Characterization of Segregation Distortion Loci on Cotton Chromosome 18.Frontiers in plant science · 2016Article
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3 authors.
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Abstract
An endogenous meiotic driver in the dengue and yellow fever vector mosquito Aedes aegypti can cause highly male-biased sex ratio distortion in crosses from suitable genetic backgrounds. We previously selected a strain that carries a strong meiotic drive gene (D) linked with the male-determining allele (M) on chromosome 1 in A. aegypti. Here, we performed segregation analysis of the M(D) locus among backcross (BC(1)) progeny from a driver male and drive-sensitive females. Assessment of sex ratios among BC(2) progeny showed ∼5.2% recombination between the M(D) locus and the sex determination locus. Multipoint linkage mapping across this region revealed consistent marker orders and recombination frequencies with the existing reference linkage map and placed the M(D) locus within a 6.5-cm interval defined by the LF159 locus and microsatellite marker 446GAA, which should facilitate future positional cloning efforts.
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