Evidence map›Paper›PMID 22307475›Full record

SynthesisNeuro-oncology2012

Systematic review of supportive care needs in patients with primary malignant brain tumors.

Elizabeth Ford, Susan Catt, Anthony Chalmers, Lesley Fallowfield

Open access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuro-oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 10 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 10 syntheses or guidelines pooled it, 219 citations in OpenAlex.

  1. A systematic review of the implementation of cancer-specific holistic needs assessment (HNA) in adult clinical practice, and applicability to the brain tumour population.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  7. Life beyond a diagnosis of glioblastoma: a systematic review of the literature.Journal of cancer survivorship : research and practice · 2017
    Pooled it
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  10. The end-of-life phase of high-grade glioma patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014
    Pooled it
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  14. Impact of consultation recordings on patient-reported outcomes in patients with brain tumors: a parallel randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  18. Coordination of care in the context of primary brain tumors: Australian healthcare professionals' exploration of the unspoken impact and clinical implications.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  20. Article

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elizabeth FordSussex Health Outcomes Research & Education in Cancer, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, United Kingdom. e.m.ford@bsms.ac.uk
Susan Catt
Anthony Chalmers
Lesley Fallowfield
Brighton and Sussex Medical School · GBUniversity of Sussex · GB

Funding

Cancer Research UK C54/A7374Medical Research Council G0802755
6 · The paper itself

Abstract

In adults, primary malignant brain tumors (PMBT) are rare, but they have a devastating impact and the chances for survival are limited. UK clinical guidance on supportive care for patients with brain and central nervous system tumors was published in 2006 and relied on very limited evidence. The current article reviews literature from 2005 through 2011 on the psychosocial and supportive needs of patients with PMBT and their families or caregivers. Searches were conducted in PubMed, Web of Science, Psychinfo, Cochrane, Scopus, ASSIA, and Sciencedirect. The search initially yielded 6220 articles, of which 60 were found to be eligible (1%). Eleven qualitative and 49 quantitative studies are reviewed here and mapped onto the structure of the existing UK clinical guidance. Studies suggest rates of depression and anxiety up to 48% in patients and up to 40% in caregivers, with many unmet needs and dissatisfaction with health care provider communication and information. Cognitive deficits increase as the disease progresses, hampering communication and decision-making. A range of neurological and physical symptoms at the end of life need recognition. Some successful supportive and neuropsychological interventions are reported. Although the volume of available studies has increased since UK guidance, many remain observational in nature, with few trials of interventions. However, this review provides an up to date resource for clinicians involved with patients with PMBT, describing current knowledge on patients' psychosocial needs, the type of care which has been found to be beneficial, and highlighting areas where more research needs to be done.

Indexed as

DepressionAnxietyBrain NeoplasmsCaregiversGliomaHumansPalliative CareQuality of Life

Identifiers

PMID22307475
PMCPMC3309849
OpenAlexW2104108691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.