ArticleCurrent biology : CB2012
Functional biases in visual cortex neurons with identified projections to higher cortical targets.
Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Early Development of Direction Selectivity in the Higher Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Morphological evidence for multiple distinct channels of corticogeniculate feedback originating in mid-level extrastriate visual areas of the ferret.Brain structure & function · 2021Article
- Development of visual motion integration involves coordination of multiple cortical stages.eLife · 2021Article
- Projections of the Mouse Primary Visual Cortex.Frontiers in neural circuits · 2021Review
- A Canonical Scheme of Bottom-Up and Top-Down Information Flows in the Frontoparietal Network.Frontiers in neural circuits · 2021Review
- Visual Response Characteristics in Lateral and Medial Subdivisions of the Rat Pulvinar.Neuroscience · 2020Article
- Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Repeated Exposure to Multiple Concurrent Stresses Induce Circuit Specific Loss of Inputs to the Posterior Parietal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Ferrets as a Model for Higher-Level Visual Motion Processing.Current biology : CB · 2019Article
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- Projection-Specific Visual Feature Encoding by Layer 5 Cortical Subnetworks.Cell reports · 2016Article
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- Structure of a single whisker representation in layer 2 of mouse somatosensory cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
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- Volitional modulation of optically recorded calcium signals during neuroprosthetic learning.Nature neuroscience · 2014Article
- Imaging neuronal populations in behaving rodents: paradigms for studying neural circuits underlying behavior in the mammalian cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Review
- Advantages of closed-loop calibration in intracortical brain-computer interfaces for people with tetraplegia.Journal of neural engineering · 2013Article
- Cortico-cortical projections in mouse visual cortex are functionally target specific.Nature neuroscience · 2013Article
- Target dependence of orientation and direction selectivity of corticocortical projection neurons in the mouse V1.Frontiers in neural circuits · 2013Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundVisual perception involves information flow from lower- to higher-order cortical areas, which are known to process different kinds of information. How does this functional specialization arise? As a step toward addressing this question, we combined fluorescent retrograde tracing with in vivo two-photon calcium imaging to simultaneously compare the tuning properties of neighboring neurons in areas 17 and 18 of ferret visual cortex that have different higher cortical projection targets.
resultsNeurons projecting to the posterior suprasylvian sulcus (PSS) were more direction selective and preferred shorter stimuli, higher spatial frequencies, and higher temporal frequencies than neurons projecting to area 21, anticipating key differences between the functional properties of the target areas themselves. These differences could not be explained by a correspondence between anatomical and functional clustering within early visual cortex, and the largest differences were in properties generated within early visual cortex (direction selectivity and length preference) rather than in properties present in its retinogeniculate inputs.
conclusionsThese projection cell groups, and hence the higher-order visual areas to which they project, likely obtain their functional properties not from biased retinogeniculate inputs but from highly specific circuitry within the cortex.
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