ArticleCell stem cell2012
Stem-cell-like qualities of immune memory; CD4+ T cells join the party.
Article in Cell stem cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Intricacies of TGF-β signaling in Treg and Th17 cell biology.Cellular & molecular immunology · 2023Review
- CD4Mediators of inflammation · 2019Article
- Memory CD4Cellular oncology (Dordrecht, Netherlands) · 2018Article
- The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis.Viruses · 2017Review
- Development and Function of Protective and Pathologic Memory CD4 T Cells.Frontiers in immunology · 2015Review
- Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4(+) T-cell subsets, including stem cell memory T-cells.Retrovirology · 2014Article
- Stem memory T cells (TSCM)-their role in cancer and HIV immunotherapies.Clinical & translational immunology · 2014Review
- Quantifying susceptibility of CD4+ stem memory T-cells to infection by laboratory adapted and clinical HIV-1 strains.Viruses · 2014Article
- Th17 cells in cancer: the ultimate identity crisis.Frontiers in immunology · 2014Review
- Eradication of HIV and Cure of AIDS, Now and How?Frontiers in immunology · 2013Review
- Review
- The Th17 family: flexibility follows function.Immunological reviews · 2013Review
- Paths to stemness: building the ultimate antitumour T cell.Nature reviews. Cancer · 2012Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
Similar to hematopoietic stem cells, memory lymphocytes self-renew, while their clonally expanded effector progeny differentiate to fight infection and tumors. Recently, Muranski et al. (2011) report in Immunity that a subset of Th17 effector cells function as memory cells and retain stem cell properties.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.