ReviewJournal of the American Academy of Dermatology2012
An overview of clinical and experimental treatment modalities for port wine stains.
Review in Journal of the American Academy of Dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Potassium Tetanyl Phosphate Laser vs Pulsed Dye Laser for Treating Port-Wine Stains - A Prospective, Split-Side Study
Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Laser and light-based treatments for port-wine birthmarks - a systematic review and network meta-analysis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025Pooled it
- Evolutionary Trends and Research Focal Points on Port Wine Stains: A Scientometric and Meta-Analysis.Journal of cosmetic dermatology · 2025Pooled it
- Therapeutic Strategies for Untreated Capillary Malformations of the Head and Neck Region: A Systematic Review and Meta-Analyses.American journal of clinical dermatology · 2021Pooled it
- Clinical Efficacy Study of 755 nm Picosecond Laser Combined With 595 nm Pulsed Dye Laser in the Treatment of Port-Wine Stain.Photodermatology, photoimmunology & photomedicine · 2026Trial
- Assessment of Outcomes With Pulsed Dye Laser Treatment of Port-Wine Stains Located Proximally vs Distally on Extremities.JAMA dermatology · 2020Trial
- Electrosclerotherapy for capillary malformations: study protocol for a randomised within-patient controlled pilot trial.BMJ open · 2017Trial
- Quantitative method for evaluation of aesthetic results after laser treatment for birthmarks.Lasers in medical science · 2013Trial
- Noninvasive Diagnosis Revealed a Strong Therapeutic Response and Skin Barrier Changes in Hemoporfin-Mediated Photodynamic Therapy for Port-Wine Stains.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026Article
- Computational modeling of oxygen dynamics in port-wine stain photodynamic therapy: treatment outcome optimization and pain management.Journal of biomedical optics · 2026Article
- Cutaneous laser treatment of port-wine stains and its impact on ocular manifestations in Sturge-Weber syndrome.Frontiers in ophthalmology · 2026Review
- Hemoporfin photodynamic therapy for port-wine stains in children: a prospective study.Frontiers in medicine · 2026Article
- Circulating Levels of VEGF, mTOR and MAPK in Patients With Port-Wine Stains.Journal of cosmetic dermatology · 2025Article
- Port-wine stain and its influence on patients' quality of life and psychosocial issues.Postepy dermatologii i alergologii · 2025Article
- Article
- Treatment of Port-Wine Birthmarks Using a Large-Spot, Variable Sequenced, Long-Pulsed KTP-Laser-A Retrospective Analysis.Journal of cosmetic dermatology · 2025Article
- Multidisciplinary, multicenter consensus for the care of patients affected with Sturge-Weber syndrome.Orphanet journal of rare diseases · 2025Article
- Photo-Mediated Ultrasound Therapy (PUT) for the Treatment of Deep Cutaneous Vasculature.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2025Article
- Optical coherence tomography-measured blood vessel characteristics of port-wine birthmarks by depth: A cross-sectional study.Journal of the American Academy of Dermatology · 2024Article
- Real-World Data on the Use of Sirolimus in Asian Children with Vascular Malformations.Paediatric drugs · 2024Article
- Current clinical evidence is insufficient to support HMME-PDT as the first choice of treatment for young children with port wine birthmarks.Lasers in surgery and medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Port wine stains (PWS) are the most common vascular malformation of the skin, occurring in 0.3% to 0.5% of the population. Noninvasive laser irradiation with flashlamp-pumped pulsed dye lasers (selective photothermolysis) currently comprises the gold standard treatment of PWS; however, the majority of PWS fail to clear completely after selective photothermolysis. In this review, the clinically used PWS treatment modalities (pulsed dye lasers, alexandrite lasers, neodymium:yttrium-aluminum-garnet lasers, and intense pulsed light) and techniques (combination approaches, multiple passes, and epidermal cooling) are discussed. Retrospective analysis of clinical studies published between 1990 and 2011 was performed to determine therapeutic efficacies for each clinically used modality/technique. In addition, factors that have resulted in the high degree of therapeutic recalcitrance are identified, and emerging experimental treatment strategies are addressed, including the use of photodynamic therapy, immunomodulators, angiogenesis inhibitors, hypobaric pressure, and site-specific pharmaco-laser therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.