Trial reportPsychosomatics
Use of complementary and alternative medicine in a large sample of anxiety patients.
Trial report in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00347269 (Coordinated Anxiety Learning and Management), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Coordinated Anxiety Learning and Management (CALM): Improving Primary Care Anxiety Outcomes
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Identifying complementary and alternative medicine recommendations for anxiety treatment and care: a systematic review and critical assessment of comprehensive clinical practice guidelines.Frontiers in psychiatry · 2023Pooled it
- A systematic review of randomized trials of mind-body interventions for PTSD.Journal of clinical psychology · 2018Pooled it
- A preliminary descriptive report of the longevity of the effects of Swedish Massage therapy for subjects with Generalized Anxiety Disorder.Journal of bodywork and movement therapies · 2023Trial
- Six versus twelve weeks of Swedish massage therapy for generalized anxiety disorder: Preliminary findings.Complementary therapies in medicine · 2021Trial
- Trial
- Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2016Trial
- Acute Swedish Massage Monotherapy Successfully Remediates Symptoms of Generalized Anxiety Disorder: A Proof-of-Concept, Randomized Controlled Study.The Journal of clinical psychiatry · 2016Trial
- Promising effects of treatment with flotation-REST (restricted environmental stimulation technique) as an intervention for generalized anxiety disorder (GAD): a randomized controlled pilot trial.BMC complementary and alternative medicine · 2016Trial
- Psychobiotic Strategies for Managing Anxiety, Depression, and Schizophrenia: A Narrative Review.Journal of restorative medicine · 2026Article
- Effect of Lavender Essential Oil-based Aromatherapy on Anxiety: An Overview of Results of Recent Randomized Controlled Trials.Current pharmaceutical design · 2026Review
- Cross-Cultural Patient Counseling and Communication in the Integrative Medicine Setting: Respecting the Patient's Health Belief Model of Care.Current psychiatry reports · 2024Review
- The Effect of Herbal Medicine on Suicidal Behavior: A Protocol for Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Article
- Understanding the Role of Oxidative Stress, Neuroinflammation and Abnormal Myelination in Excessive Aggression Associated with Depression: Recent Input from Mechanistic Studies.International journal of molecular sciences · 2023Review
- Self-treatment and adverse reactions with herbal products for treating symptoms associated with anxiety and depression in adults from the central-western region of Mexico during the Covid-19 pandemic.Journal of ethnopharmacology · 2021Article
- Increased Oxidative Stress in the Prefrontal Cortex as a Shared Feature of Depressive- and PTSD-Like Syndromes: Effects of a Standardized Herbal Antioxidant.Frontiers in nutrition · 2021Article
- Self-care for anxiety and depression: a comparison of evidence from Cochrane reviews and practice to inform decision-making and priority-setting.BMC complementary medicine and therapies · 2020Article
- An Integrative Model for the Effectiveness of Biofeedback Interventions for Anxiety Regulation: Viewpoint.Journal of medical Internet research · 2020Article
- Yoga practice in the UK: a cross-sectional survey of motivation, health benefits and behaviours.BMJ open · 2020Article
- Perspectives on the use of aromatherapy from clinicians attending an integrative medicine continuing education event.BMC complementary and alternative medicine · 2019Article
- Complementary and alternative medicine contacts by persons with mental disorders in 25 countries: results from the World Mental Health Surveys.Epidemiology and psychiatric sciences · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectiveTo examine a large sample of patients with anxiety and the association between types of complementary and alternative treatments that were used, demographic variables, diagnostic categories, and treatment outcomes.
methodCross-sectional and longitudinal survey during the Coordinated Anxiety Learning and Management (CALM) study that assessed this intervention against the Usual Care in a sample of patients with anxiety recruited from primary care. Interviewer-administered questionnaires via a centralized telephone survey by blinded assessment raters. The interviews were done at baseline, 6, 12, and 18 months of the study. A total of 1004 adults ages 18-75 who met DSM-IV criteria for Generalized Anxiety Disorder (GAD), Panic Disorder, Social Anxiety Disorder, or Post-Traumatic Stress Disorder. We assessed medication/herbal use, the use of any alternative therapies, and combined Complementary and Alternative Medicine (CAM) use.
resultsWe found an extensive (43%) use of a variety of CAM treatments that is consistent with previous study results in populations with anxiety. Only a few significant demographic or interventional characteristics of CAM users were found. Users most often had a diagnosis of GAD, were older, more educated, and had two or more chronic medical conditions. CAM users who had a 50% or more drop in anxiety scores over 18 months were less likely to report continued use of alternative therapies.
conclusionsThe study confirms the importance of awareness of CAM use in this population for possible interference with traditional first-line treatments of these disorders, but also for finding the best integrative use for patients who require multiple treatment modalities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.