Evidence map›Paper›PMID 22304732›Full record

ArticleEmerging infectious diseases2012

Diphtheria in the postepidemic period, Europe, 2000-2009.

Karen S Wagner, Joanne M White, Irina Lucenko, David Mercer, Natasha S Crowcroft, Shona Neal, Androulla Efstratiou, Diphtheria Surveillance Network

Registry-linked trialAbstract read
In one paragraph

Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05798247 (Cutaneous Diphtheria in France), which is not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05798247 completednot on this mapstarted 2023, after this paper: background citation

Cutaneous Diphtheria in France : an Observational, Retrospective Study of Epidemiological, Clinical, Microbiological and Therapeutic Characteristics

TypeobservationalSponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2023 to 2023Enrolled63ConditionsCorynebacterium Diphtheriae InfectionArmsCharacteristics description
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Bacterial AB toxins and host-microbe interactions.Advances in microbial physiology · 2022
    Review
  16. Describing the burden of diphtheria in Canada from 2006 to 2017, using hospital administrative data and reportable disease data.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
    Article
  17. Review
  18. Article
  19. Trend in mandatory immunisation coverage: linear and joinpoint regression approach, Serbia, 2000 to 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karen S WagnerHealth Protection Agency, London, UK. karen.wagner@hpa.org.uk
Joanne M White
Irina Lucenko
David Mercer
Natasha S Crowcroft
Shona Neal
Androulla Efstratiou
Diphtheria Surveillance Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diphtheria incidence has decreased in Europe since its resurgence in the 1990s, but circulation continues in some countries in eastern Europe, and sporadic cases have been reported elsewhere. Surveillance data from Diphtheria Surveillance Network countries and the World Health Organization European Region for 2000-2009 were analyzed. Latvia reported the highest annual incidence in Europe each year, but the Russian Federation and Ukraine accounted for 83% of all cases. Over the past 10 years, diphtheria incidence has decreased by >95% across the region. Although most deaths occurred in disease-endemic countries, case-fatality rates were highest in countries to which diphtheria is not endemic, where unfamiliarity can lead to delays in diagnosis and treatment. In western Europe, toxigenic Corynebacterium ulcerans has increasingly been identified as the etiologic agent. Reduction in diphtheria incidence over the past 10 years is encouraging, but maintaining high vaccination coverage is essential to prevent indigenous C. ulcerans and reemergence of C. diphtheriae.

Indexed as

EpidemicsAdolescentAdultChildChild, PreschoolCorynebacteriumDiphtheriaEuropeFemaleHumansIncidenceInfantMaleMiddle AgedPopulation SurveillanceVaccination

Identifiers

PMID22304732
PMCPMC3310452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.