Evidence map›Paper›PMID 22304713›Full record

ReviewCurrent medicinal chemistry2012

GCPII imaging and cancer.

C A Foss, R C Mease, S Y Cho, H J Kim, M G Pomper

Open access · bronzeAbstract readReview
In one paragraph

Review in Current medicinal chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 78 citations in OpenAlex.

  1. European journal of nuclear medicine and molecular imaging · 2019
    Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Design, preclinical evaluation, and first-in-human PET study of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  7. Fully Automated Production of (((Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. PSMA-Targeted PET Radiotracer [Clinical and experimental gastroenterology · 2023
    Article
  15. Review
  16. [Scientific reports · 2022
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C A FossRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical School, Baltimore, MD 21231, USA.
R C Mease
S Y Cho
H J Kim
M G Pomper
Johns Hopkins University · US

Funding

PSMA-based Cancer Imaging AgentsR01CA134675 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G · 2009 to 2025
$6.2M
Interdisciplinary Small Animal Imaging for OncologyR24CA092871 · NCI · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G · 2001 to 2006
$5.1M
Small Animal Imaging Resource (SAIR)U24CA092871 · NCI · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G · 2007 to 2011
$2.3M
NCI NIH HHS CA134675NCI NIH HHS CA92871NCI NIH HHS R01 CA134675NCI NIH HHS R24 CA092871NCI NIH HHS U24 CA092871
6 · The paper itself

Abstract

Glutamate carboxypeptidase II (GCPII) in the central nervous system is referred to as the prostate-specific membrane antigen (PSMA) in the periphery. PSMA serves as a target for imaging and treatment of prostate cancer and because of its expression in solid tumor neovasculature has the potential to be used in this regard for other malignancies as well. An overview of GCPII/PSMA in cancer, as well as a discussion of imaging and therapy of prostate cancer using a wide variety of PSMA-targeting agents is provided.

Indexed as

Antigens, SurfaceGlutamate Carboxypeptidase IIAnimalsGene Expression Regulation, NeoplasticGlutamic AcidHumansMaleMolecular ImagingNeoplasmsProstateProstatic NeoplasmsAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IIGlutamic Acid

Identifiers

PMID22304713
PMCPMC4076792
OpenAlexW2126741950

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.