ArticleFrontiers in genetics2011
Epigenomics in environmental health.
Article in Frontiers in genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 115 citations in OpenAlex.
- Nutrition, Environment, and Genetics in Colorectal Cancer. Epigenetics and Possible Future Perspective.Current nutrition reports · 2025Review
- Linking Benzene, in Utero Carcinogenicity and Fetal Hematopoietic Stem Cell Niches: A Mechanistic Review.International journal of molecular sciences · 2023Review
- Promoter methylation analysis ofAsian biomedicine : research, reviews and news · 2022Article
- 10 Years of Toxicogenomics section in Frontiers in Genetics: Past discoveries and Future Perspectives.Frontiers in genetics · 2022Review
- Review
- Adiponectin DNA methylation in South African women with gestational diabetes mellitus: Effects of HIV infection.PloS one · 2021Article
- No Association BetweenDiabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS.Epigenetics · 2020Article
- Ionizing Radiation-Induced Epigenetic Modifications and Their Relevance to Radiation Protection.International journal of molecular sciences · 2020Review
- Article
- The Response of Living Organisms to Low Radiation Environment and Its Implications in Radiation Protection.Frontiers in public health · 2020Review
- Ethnic and Adipose Depot Specific Associations Between DNA Methylation and Metabolic Risk.Frontiers in genetics · 2020Article
- Environmental Endocrine-Disrupting Chemical Exposure: Role in Non-Communicable Diseases.Frontiers in public health · 2020Review
- Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration.Cancer prevention research (Philadelphia, Pa.) · 2019Article
- An epigenome-wide analysis of cord blood DNA methylation reveals sex-specific effect of exposure to bisphenol A.Scientific reports · 2019Article
- Nutrigenetics, epigenetics and gestational diabetes: consequences in mother and child.Epigenetics · 2019Review
- Cancer in wildlife: patterns of emergence.Nature reviews. Cancer · 2018Review
- Global and gene-specific DNA methylation in adult type 2 diabetic individuals: a protocol for a systematic review.Systematic reviews · 2018Article
- Epigenetic Inheritance: Concepts, Mechanisms and Perspectives.Frontiers in molecular neuroscience · 2018Article
- Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight.BMC public health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
This review considers the emerging relationships between environmental factors and epigenetic alterations and the application of genome-wide assessments to better define these relationships. First we will briefly cover epigenetic programming in development, one-carbon metabolism, and exposures that may disrupt normal developmental programming of epigenetic states. In addition, because a large portion of epigenetic research has focused on cancer, we discuss exposures associated with carcinogenesis including asbestos, alcohol, radiation, arsenic, and air pollution. Research on other exposures that may affect epigenetic states such as endocrine disruptors is also described, and we also review the evidence for epigenetic alterations associated with aging that may reflect cumulative effects of exposures. From this evidence, we posit potential mechanisms by which exposures modify epigenetic states, noting that understanding the true effect of environmental exposures on the human epigenome will require additional research with appropriate epidemiologic studies and application of novel technologies. With a more comprehensive understanding of the affects of exposures on the epigenome, including consideration of genetic background, the prediction of the toxic potential of new compounds may be more readily achieved, and may lead to the development of more personalized disease prevention and treatment strategies.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.