Evidence map›Paper›PMID 22303287›Full record

ArticlePLoS medicine2012

Hitting hotspots: spatial targeting of malaria for control and elimination.

Teun Bousema, Jamie T Griffin, Robert W Sauerwein, David L Smith, Thomas S Churcher, Willem Takken, Azra Ghani, Chris Drakeley, Roly Gosling

4 registry-linked trialsAbstract read
In one paragraph

Article in PLoS medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 382 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
382citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01575613 nacompletednot on this map

Reducing the Burden of Malaria by Targeting Hotspots of Transmission and Improving Malaria Control Measures in the Highlands of Western Kenya: Simultaneous Rollout of Four Malaria Control Interventions and Evaluation by Cross-sectional Surveys

TypeinterventionalSponsorRadboud University Medical CenterRan2012 to 2012Enrolled17,506ConditionsMalariaArmsArtemether-lumefantrine combination, Bacillus thuringiensis, Long lasting insecticide treated net (LLINs), Indoor Residual Spraying (IRS)
NCT02610400 phase3completednot on this mapstarted 2016, after this paper: background citation

Targeted Parasite Elimination in the Human and Mosquito to Reduce Malaria Transmission: A Cluster Randomised Controlled Factorial Design Trial of Reactive Focal Drug Administration (rfMDA) Versus Reactive Case Detection (RACD), With and Without Reactive Vector Control (RAVC), From the Low Endemic Setting of Namibia

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2017Enrolled9,845ConditionsMalariaArmsRACD, RAVC, rfMDA
NCT04416945 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

Targeting High-risk Populations With Enhanced Reactive Case Detection: a Study to Assess the Effectiveness and Feasibility for Reducing Plasmodium Falciparum and P. Vivax Malaria in Southern Lao Peoples Democratic Republic

TypeinterventionalSponsorUniversity of California, San FranciscoRan2020 to 2021Enrolled0ConditionsPlasmodium Falciparum Malaria, Plasmodium Vivax MalariaArmsHousehold Reactive Case Detection, RACD of cases' co-workers/co-travelers, Case Management and Follow-up
NCT05052502 nacompletednot on this mapstarted 2020, after this paper: background citation

Targeting High-risk Populations With Enhanced Reactive Focal Mass Drug Administration: A Study to Assess the Effectiveness and Feasibility for Plasmodium Falciparum and Plasmodium Vivax Malaria in Thailand

TypeinterventionalSponsorUniversity of California, San FranciscoRan2020 to 2022Enrolled14,977ConditionsPlasmodium Falciparum Malaria, Plasmodium Vivax MalariaArmsCase Management and Follow-up, Reactive focal mass drug administration (rfMDA)
3 · Its place in the literature

Who cites it

382 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. House modifications for preventing malaria.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Pooled it
  3. House modifications for preventing malaria.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Pooled it
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  7. Trial
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  13. The American journal of tropical medicine and hygiene · 2018
    Trial
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  15. Article
  16. SubmicroscopicTropical medicine and infectious disease · 2026
    Article
  17. Review
  18. Review
  19. Territorial Persistence of ResidualTropical medicine and infectious disease · 2026
    Article
  20. Article

322 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Teun BousemaDepartment of Immunity and Infection, London School of Hygiene & Tropical Medicine, London, United Kingdom. teun.bousema@lshtm.ac.uk
Jamie T Griffin
Robert W Sauerwein
David L Smith
Thomas S Churcher
Willem Takken
Azra Ghani
Chris Drakeley
Roly Gosling

Funding

Medical Research Council G1002284Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mosquito ControlDisease EradicationHumansMalaria

Identifiers

PMID22303287
PMCPMC3269430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.