ArticleThe arabidopsis book2010
Proline metabolism and its implications for plant-environment interaction.
Article in The arabidopsis book, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 216 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
216 citing papers in PubMed, 594 citations in OpenAlex.
- Evolutionary and Structural Insights into Proline Metabolism Genes Associated with Salt Resilience in Mango.Biochemical genetics · 2026Article
- DELLA proteins enhance cadmium tolerance by coordinating redox protection and cadmium partitioning in Arabidopsis.Planta · 2026Article
- Nitrogen Mediates Amino Acid Metabolism Affecting Stachydrine Synthesis inPlants (Basel, Switzerland) · 2026Article
- Proline Dehydrogenase GeneJournal of fungi (Basel, Switzerland) · 2026Article
- Revealing Functional Traits of Insect Pest Suppressive Rhizobacterial Strains Through Comparative Genomics.Environmental microbiology · 2026Article
- The meiotic achilles' heel: vulnerability and resilience under environmental stress.Protoplasma · 2026Review
- Adaptive Responses of Tropical Crops: A Multi-Scale Omics Integrated Perspective.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A comparative study of the growth, yield, and physiological responses of arbosana, arbequina, coratina, and maraqi olive cultivars.Scientific reports · 2026Article
- Compatible Solute Variation and Stress Adaptation in Native Qatari Plants: Focus on Proline.Life (Basel, Switzerland) · 2026Review
- Beyond osmoprotection: the expanding roles of proline in plant signalling and development.Biologia futura · 2026Review
- Glycine Betaine-Induced Metabolic Responses Under Heat and Cold Stress inInternational journal of molecular sciences · 2026Article
- Environmental stress reveals new insights regarding proteome rebalancing in Arabidopsis thaliana seeds.The Plant journal : for cell and molecular biology · 2026Article
- Review
- Drought tolerance mechanisms across C3 and C3-C4 intermediate photosynthetic types revealed by physiological and gene expression profiling.Scientific reports · 2026Article
- Dendrogenomic resilience mechanisms of two endangered Mexican spruces.Plant diversity · 2026Article
- Integrated physiological, photochemical and anatomical responses reveal divergent drought-response strategies among herbaceous peony cultivars.Frontiers in plant science · 2026Article
- Redox homeostasis under summer stress: targeted ROS modulation by foliar kaolin-silicon mixtures inFrontiers in plant science · 2026Article
- Early physiological and biochemical modulation in garlic under drought and high temperature.Frontiers in plant science · 2026Article
- Antiviral potential of crude extracts from two Streptomyces spp. against Cucumber Mosaic Virus infection under greenhouse conditions.Scientific reports · 2025Article
- Role of Bacillus subtilis W1L in Mitigating Oxidative and Osmotic Stress in Lettuce under Drought and Salt Conditions.The plant pathology journal · 2025Article
156 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proline has long been known to accumulate in plants experiencing water limitation and this has driven studies of proline as a beneficial solute allowing plants to increase cellular osmolarity during water limitation. Proline metabolism also has roles in redox buffering and energy transfer and is involved in plant pathogen interaction and programmed cell death. Some of these unique roles of proline depend on the properties of proline itself, whereas others depend on the "proline cycle" of coordinated proline synthesis in the chloroplast and cytoplasm with proline catabolism in the mitochondria. The regulatory mechanisms controlling proline metabolism, intercellular and intracellular transport and connections of proline to other metabolic pathways are all important to the in vivo functions of proline metabolism. Connections of proline metabolism to the oxidative pentose phosphate pathway and glutamate-glutamine metabolism are of particular interest. The N-acetyl glutamate pathway can also produce ornithine and, potentially, proline but its role and activity are unclear. Use of model systems such as Arabidopsis thaliana to better understand both these long studied and newly emerging functions of proline can help in the design of next-generation experiments testing whether proline metabolism is a promising metabolic engineering target for improving stress resistance of economically important plants.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.