ArticleThe arabidopsis book2009
Aspartate-Derived Amino Acid Biosynthesis in Arabidopsis thaliana.
Article in The arabidopsis book, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 94 citations in OpenAlex.
- Amino Acids as Multifunctional Molecules in Plants: From Fundamental Metabolism to Precision Agriculture.Plants (Basel, Switzerland) · 2026Review
- TPM-like manipulations exerted an antidepressant effect and regulated amino acid metabolism and GHR/IGF-1 pathway in the liver in adolescent female CUMS rats.Frontiers in physiology · 2026Article
- Comprehensive Review of L-Lysine: Chemistry, Occurrence, and Physiological Roles.Current protein & peptide science · 2026Review
- Tissue-specific amino acid accumulation in Cynomorium songaricum stem and epidermis responds to distinct water and soil cues.PloS one · 2026Article
- RETICULATA1 is a plastid-localized basic amino acid transporter.Nature plants · 2025Article
- Loss of Arabidopsis ACR11 results in altered C/N balance and high sensitivity to nitrogen toxicity.Frontiers in plant science · 2025Article
- Transcriptomic characterization of recombinantApplied and environmental microbiology · 2024Article
- Integrative physiological, metabolomic, and transcriptomic analysis reveals the drought responses of two apple rootstock cultivars.BMC plant biology · 2024Article
- Tissue distribution of metabolites in Cordyceps cicadae determined by DESI-MSI analysis.Analytical and bioanalytical chemistry · 2024Article
- OverexpressingInternational journal of molecular sciences · 2023Article
- Prebiotic Synthesis of Aspartate Using Life's Metabolism as a Guide.Life (Basel, Switzerland) · 2023Article
- Genetic dissection reveals the complex architecture of amino acid composition in soybean seeds.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- A mutation in THREONINE SYNTHASE 1 uncouples proliferation and transition domains of the root apical meristem: experimental evidence and in silico proposed mechanism.Development (Cambridge, England) · 2022Article
- Proteomics approach to investigating osmotic stress effects on pistachio.Frontiers in plant science · 2022Article
- Genome-Wide Identification and Characterization of Long Noncoding RNAs inFrontiers in plant science · 2022Article
- Identification and Functional Prediction of Poplar Root circRNAs Involved in Treatment With Different Forms of Nitrogen.Frontiers in plant science · 2022Article
- Interkingdom Comparison of Threonine Metabolism for Stem Cell Maintenance in Plants and Animals.Frontiers in cell and developmental biology · 2021Review
- Genotypic Variation of Nitrogen Use Efficiency and Amino Acid Metabolism in Barley.Frontiers in plant science · 2021Article
- Article
- Root Metabolite Differences in Two Maize Varieties Under Lead (Pb) Stress.Frontiers in plant science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aspartate-derived amino acid pathway in plants leads to the biosynthesis of lysine, methionine, threonine, and isoleucine. These four amino acids are essential in the diets of humans and other animals, but are present in growth-limiting quantities in some of the world's major food crops. Genetic and biochemical approaches have been used for the functional analysis of almost all Arabidopsis thaliana enzymes involved in aspartate-derived amino acid biosynthesis. The branch-point enzymes aspartate kinase, dihydrodipicolinate synthase, homoserine dehydrogenase, cystathionine gamma synthase, threonine synthase, and threonine deaminase contain well-studied sites for allosteric regulation by pathway products and other plant metabolites. In contrast, relatively little is known about the transcriptional regulation of amino acid biosynthesis and the mechanisms that are used to balance aspartate-derived amino acid biosynthesis with other plant metabolic needs. The aspartate-derived amino acid pathway provides excellent examples of basic research conducted with A. thaliana that has been used to improve the nutritional quality of crop plants, in particular to increase the accumulation of lysine in maize and methionine in potatoes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.