Evidence map›Paper›PMID 22303242›Full record

ArticleThe arabidopsis book2008

Sugar sensing and signaling.

Matthew Ramon, Filip Rolland, Jen Sheen

Open access · bronzeAbstract read
In one paragraph

Article in The arabidopsis book, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 222 citations in OpenAlex.

  1. Review
  2. Sugar-sensing swodkoreceptors and swodkocrine signaling.Animal models and experimental medicine · 2025
    Article
  3. Transcriptome and MicroRNA Analysis ofInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Plant Heterotrophic Cultures: No Food, No Growth.Plants (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. OsHXK3 encodes a hexokinase-like protein that positively regulates grain size in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Retention of freshness and isothiocyanates in fresh-cut radish (Journal of food science and technology · 2022
    Article
  17. Review
  18. Review
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Matthew Ramon
Filip Rolland
Jen Sheen
Czech Academy of Sciences, Institute of Botany · CZHarvard University · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants, restricted by their environment, need to integrate a wide variety of stimuli with their metabolic activity, growth and development. Sugars, generated by photosynthetic carbon fixation, are central in coordinating metabolic fluxes in response to the changing environment and in providing cells and tissues with the necessary energy for continued growth and survival. A complex network of metabolic and hormone signaling pathways are intimately linked to diverse sugar responses. A combination of genetic, cellular and systems analyses have uncovered nuclear HXK1 (hexokinase1) as a pivotal and conserved glucose sensor, directly mediating transcription regulation, while the KIN10/11 energy sensor protein kinases function as master regulators of transcription networks under sugar and energy deprivation conditions. The involvement of disaccharide signals in the regulation of specific cellular processes and the potential role of cell surface receptors in mediating sugar signals add to the complexity. This chapter gives an overview of our current insight in the sugar sensing and signaling network and describes some of the molecular mechanisms involved.

Identifiers

PMID22303242
PMCPMC3243355
OpenAlexW2125989300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.