Trial reportEnvironmental health and preventive medicine2012
Environmental intervention for house dust mite control in childhood bronchial asthma.
Trial report in Environmental health and preventive medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review.BMJ open · 2014Pooled it
- Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Trial
- Efficacy of an in-home test kit in reducing dust mite allergen levels: results of a randomized controlled pilot study.The Journal of asthma : official journal of the Association for the Care of Asthma · 2016Trial
- Prevalence of food and inhalant allergies in infants and children from the Nanhai area of Foshan city.BMC pediatrics · 2025Article
- House dust mite allergen avoidance strategies for the treatment of allergic asthma: A hypothesis-generating meta-analysis.The World Allergy Organization journal · 2024Review
- Hydrolyzable Tannins in the Management of Th1, Th2 and Th17 Inflammatory-Related Diseases.Molecules (Basel, Switzerland) · 2022Review
- 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group.The Journal of allergy and clinical immunology · 2020Review
- A meta-analysis of baseline characteristics in trials on mite allergen avoidance in asthmatics: room for improvement.Clinical and translational allergy · 2020Review
- Inner-City Asthma in Children.Clinical reviews in allergy & immunology · 2019Review
- Genome-wide interaction study of dust mite allergen on lung function in children with asthma.The Journal of allergy and clinical immunology · 2017Article
- Article
- Particularities of allergy in the Tropics.The World Allergy Organization journal · 2016Review
- Sensitization Rates for Various Allergens in Children with Allergic Rhinitis in Qingdao, China.International journal of environmental research and public health · 2015Article
- Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine.Environmental health perspectives · 2015Review
- The indoor environment and inner-city childhood asthma.Asian Pacific journal of allergy and immunology · 2014Review
- Environmental remediation in the treatment of allergy and asthma: latest updates.Current allergy and asthma reports · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study was carried out to determine the effectiveness of physical and chemical environmental control measures for house dust mites (HDM) in controlling bronchial asthma in children.
methodsA total of 160 asthmatic children who were sensitized to HDM underwent clinical and environmental assessment. The children were randomly allocated into one of four groups according to the intervention (chemical, physical, both chemical and physical, none) and the effectiveness of the intervention was assessed at 8 and 16 weeks.
resultsThe group for which physical control measures were used showed significant improvement in all outcome measures, including mean differences of forced expiratory volume after 1 s (FEV1) and peak expiratory flow rate (PEFR), which were 2.05% and 4.65 l/min, respectively, at the 8-week follow-up evaluation. The percentage of severe asthma decreased from 45 to 22%. Similar results were obtained for the group with both chemical (tannic acid) and physical interventions (p < 0.05 for all measures). In the group where tannic acid was used as a chemical measure, the number of children with moderate and severe asthma decreased from 15 in each category to 11 and 7, respectively. In the control group, only the mean difference of PEFR (1.62 l/min) was significant after 16 weeks. Despite these promising findings, only the FEV1 was significantly different (p = 0.014) when the four groups were compared.
conclusionsBased on these results, we conclude that simple physical control measures have the potential to contribute to the control of asthma symptoms in asthmatic children sensitized to HDM allergen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.