ArticlePediatric radiology2012
Rapidly involuting congenital haemangioma (RICH) of the liver.
Article in Pediatric radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- A Comprehensive Review of Hepatic Hemangioma Management.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Pooled it
- Clinical features and management of multifocal hepatic hemangiomas in children: a retrospective study.Scientific reports · 2016Trial
- Non-Involuting Congenital Hepatic Hemangioma: Lessons from a Case Series.Children (Basel, Switzerland) · 2025Article
- Clinical characteristics and managements of congenital hepatic hemangioma: a cohort study of 211 cases.Hepatology international · 2025Observational
- Hepatic hemangiomas mimicking gastrointestinal stromal tumors: A case report.World journal of clinical cases · 2025Article
- Complete regression of a huge fetal hepatic hemangioma with cardiac complication after atrioventricular septal repair: a case description and literature analysis.Quantitative imaging in medicine and surgery · 2025Article
- Postnatal treatment and evolution patterns of giant fetal hepatic hemangioma: a case series of 29 patients.BMC pediatrics · 2024Article
- Pediatric hepatic hemangiomas: spectrum and prognostic significance of initial ultrasound findings.Pediatric radiology · 2023Article
- Conservative management of congenital hepatic hemangioma complicated by ascites.Clinical case reports · 2022Article
- Spontaneous evolution patterns of focal congenital hepatic hemangiomas: a case series of 25 patients.Pediatric radiology · 2022Article
- Infantile hepatic hemangiomas: looking backwards and forwards.Precision clinical medicine · 2022Review
- Pediatric vascular tumors of the liver: Review from the pathologist's point of view.World journal of hepatology · 2021Review
- Computed tomography imaging and clinical features of congenital hepatoblastoma: A retrospective analysis.Medicine · 2020Article
- Rapidly involuting congenital haemangioma of the liver.BMJ case reports · 2018Article
- Advances in the Medical Management of Vascular Anomalies.Seminars in interventional radiology · 2017Review
- The changing face of complicated infantile hemangioma treatment.Pediatric radiology · 2016Review
- RICH depuis la lettre.Pediatric radiology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRapidly involuting congenital haemangioma (RICH) is a benign neoplasm that may occur in many locations in the body. When RICH occurs in the liver, it may be confused with other lesions.
objectiveTo present a case series from a single institution. MATERIALS AND
methodsRetrospective review of pathological and imaging findings in infants with biopsy-proven hepatic RICH treated at a single hospital.
resultsFour children (2 days to 6 weeks of age) presented between 2002 and 2007 with a solitary hepatic lesion. Needle biopsy excluded the alternative possibility of infantile haemangioma by showing negativity for GLUT1. Serial imaging confirmed rapid involution in each child.
conclusionRICH should be suspected in neonates who present with a solitary liver lesion and normal-for-age serum alpha-fetoprotein. Serial US scans should be used to confirm a progressive shrinkage of the lesion. Corticosteroids and β2-adrenergic antagonists have no proven effect in treating RICH. If the lesion grows, percutaneous needle biopsy is recommended to exclude a malignant tumour and to direct further management. Infants with cardiac failure should be treated medically. Embolization (with or without needle biopsy) should only be performed when this strategy fails.
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