Evidence map›Paper›PMID 22301929›Full record

Trial reportThe American journal of clinical nutrition2012

Replacing caloric beverages with water or diet beverages for weight loss in adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial.

Deborah F Tate, Gabrielle Turner-McGrievy, Elizabeth Lyons, June Stevens, Karen Erickson, Kristen Polzien, Molly Diamond, Xiaoshan Wang, Barry Popkin

Erratum issued 2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 171 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
171citing papers in PubMed, 18 pooled it
19.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01017783 nacompletednot on this map

Randomized Controlled Trial of a Water Beverage Intervention for Promoting Modest Weight Reduction in Free Living Adults

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2008 to 2010Enrolled318ConditionsObesityArmsDietary substitution A, Dietary Substitution B, Healthy Choices
NCT02877823 nacompletednot on this mapstarted 2016, after this paper: background citation

A Community-based, Family Navigator Intervention to Improve Cardiometabolic Health of Medicaid-insured Youth Identified Through an Antipsychotic Medication Preauthorization Program

TypeinterventionalSponsorUniversity of Maryland, BaltimoreRan2016 to 2021Enrolled302ConditionsChildhood ObesityArmsTreatment, Control
3 · Its place in the literature

Who cites it

171 citing papers in PubMed, 18 syntheses or guidelines pooled it, 341 citations in OpenAlex.

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  9. Long-term effects of weight-reducing diets in people with hypertension.The Cochrane database of systematic reviews · 2021
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  15. Long-term effects of weight-reducing diets in people with hypertension.The Cochrane database of systematic reviews · 2016
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111 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Deborah F TateDepartment of Nutrition, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7440, USA. dtate@unc.edu
Gabrielle Turner-McGrievy
Elizabeth Lyons
June Stevens
Karen Erickson
Kristen Polzien
Molly Diamond
Xiaoshan Wang
Barry Popkin
University of North Carolina at Chapel Hill · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
NIA NIH HHS P30 AG024832NICHD NIH HHS R24 HD050924NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

backgroundReplacement of caloric beverages with noncaloric beverages may be a simple strategy for promoting modest weight reduction; however, the effectiveness of this strategy is not known.

objectiveWe compared the replacement of caloric beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo in adults and attention controls (ACs).

designOverweight and obese adults [n = 318; BMI (in kg/m(2)): 36.3 ± 5.9; 84% female; age (mean ± SD): 42 ± 10.7 y; 54% black] substituted noncaloric beverages (water or DBs) for caloric beverages (≥200 kcal/d) or made dietary changes of their choosing (AC) for 6 mo.

resultsIn an intent-to-treat analysis, a significant reduction in weight and waist circumference and an improvement in systolic blood pressure were observed from 0 to 6 mo.Mean ((±SEM) weight losses at 6 mo were -2.5 ± 0.45% in the DB group, -2.03 ± 0.40% in the water group, and -1.76 ± 0.35% in the AC group; there were no significant differences between groups [corrected]. The chance of achieving a 5% weight loss at 6 mo was greater in the DB group than in the AC group (OR: 2.29; 95% CI: 1.05, 5.01; P = 0.04). A significant reduction in fasting glucose at 6 mo (P = 0.019) and improved hydration at 3 (P = 0.0017) and 6 (P = 0.049) mo was observed in the Water group relative to the AC group. In a combined analysis, participants assigned to beverage replacement were 2 times as likely to have achieved a 5% weight loss (OR: 2.07; 95% CI: 1.02, 4.22; P = 0.04) than were the AC participants.

conclusionsReplacement of caloric beverages with noncaloric beverages as a weight-loss strategy resulted in average weight losses of 2% to 2.5%. This strategy could have public health significance and is a simple, straightforward message. This trial was registered at clinicaltrials.gov as NCT01017783.

Indexed as

BeveragesFeeding BehaviorWeight LossAdultBlood GlucoseBlood PressureChoice BehaviorDietDiet, ReducingEnergy IntakeFastingFemaleFollow-Up StudiesHumansInterviews as TopicLogistic ModelsBlood GlucoseWater

Identifiers

PMID22301929
PMCPMC3632875
OpenAlexW2165702513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.