Evidence map›Paper›PMID 22301530›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2012

Effect of heparin and other factors associated with complications of peripherally inserted central venous catheters in neonates.

B Isemann, R Sorrels, H Akinbi

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. [Operation and management guidelines for peripherally inserted central catheter in neonates (2021)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
    Article
  7. Article
  8. Peripherally inserted central catheter tip position and risk of associated complications in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2013
    Article
  9. Article
  10. Article
  11. [Obstruction of peripherally inserted central catheters in newborns: prevention is the best intervention].Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

B IsemannDepartment of Pharmacy, UCHealth University Hospital, Cincinnati, OH, USA. barbara.isemann@uchealth.com
R Sorrels
H Akinbi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify factors associated with complications necessitating unplanned removal of peripherally inserted central venous catheters (PICCs) in neonates. STUDY

designA before-and-after comparison following the exclusion of heparin from continuous infusions through PICCs placed by a designated team. Duration of use was assessed during epochs immediately preceding and following the practice change. Multivariable logistic regression was performed to identify independent risk factors associated with unplanned catheter removal.

resultWe analyzed 189 PICC placements with heparin (epoch 1) and 188 with no heparin (epoch 2) added to infusions. Rates of complication (23.7 vs 17.2 per 1000 catheter days) and median durations of use (7 vs 8 days) did not differ significantly between the epochs. Non-central position of the catheter tip, use of dual lumen catheters and placement through the cephalic vein were independently associated with complications (each P<0.05).

conclusionIn neonates requiring short-term intravenous access, heparin may be safely omitted from continuous infusions without compromising catheter usability.

Indexed as

AnticoagulantsCatheterization, Central VenousCentral Venous CathetersEquipment DesignHeparinHumansInfantInfant, NewbornInfusions, IntravenousLogistic ModelsRisk FactorsAnticoagulantsHeparin

Identifiers

PMID22301530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.