Evidence map›Paper›PMID 22300977›Full record

ReviewCold Spring Harbor perspectives in biology2012

Building muscle: molecular regulation of myogenesis.

C Florian Bentzinger, Yu Xin Wang, Michael A Rudnicki

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 658 papers.

0numbers the graph read from it
0cells of the map it votes in
658citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05671614 recruitingnot on this mapstarted 2022, after this paper: background citation

Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure?

TypeobservationalSponsorCharles University, Czech RepublicRan2022 to 2025Enrolled50ConditionsIntensive Care Unit-acquired Weakness
NCT05879575 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects and Pathophysiology of Weight Training on Pregnancy-related Pelvic Girdle Pain (PPGP)

TypeinterventionalSponsorNational Taiwan University Hospital Hsin-Chu BranchRan2023 to 2024Enrolled70ConditionsPelvic Girdle PainArmsweight training
3 · Its place in the literature

Who cites it

658 citing papers in PubMed, 1,165 citations in OpenAlex.

  1. Article
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  5. Review
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  9. Review
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  11. A causal SNP in the promoter ofZoological research · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

598 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

C Florian BentzingerThe Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada.
Yu Xin Wang
Michael A Rudnicki
Stem Cell Network · CAUniversity of Ottawa · CA

Funding

Canadian Institutes of Health ResearchHoward Hughes Medical Institute
6 · The paper itself

Abstract

The genesis of skeletal muscle during embryonic development and postnatal life serves as a paradigm for stem and progenitor cell maintenance, lineage specification, and terminal differentiation. An elaborate interplay of extrinsic and intrinsic regulatory mechanisms controls myogenesis at all stages of development. Many aspects of adult myogenesis resemble or reiterate embryonic morphogenetic episodes, and related signaling mechanisms control the genetic networks that determine cell fate during these processes. An integrative view of all aspects of myogenesis is imperative for a comprehensive understanding of muscle formation. This article provides a holistic overview of the different stages and modes of myogenesis with an emphasis on the underlying signals, molecular switches, and genetic networks.

Indexed as

AnimalsFemaleHumansMuscle DevelopmentMuscle ProteinsMuscle, SkeletalPregnancyStem CellsMuscle Proteins

Identifiers

PMID22300977
PMCPMC3281568
OpenAlexW2156131965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.