Evidence map›Paper›PMID 22300350›Full record

ReviewBritish journal of clinical pharmacology2012

Does it matter where we measure blood pressure?

Laurie A Tomlinson, Ian B Wilkinson

Abstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Blood pressure as a drug target: what should we be measuring?British journal of clinical pharmacology · 2012
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Laurie A TomlinsonClinical Pharmacology Unit, Addenbrooke's Hospital, Cambridge, UK. lat42@cam.ac.uk
Ian B Wilkinson

Funding

British Heart Foundation FS/12/8/29377
6 · The paper itself

Abstract

Although blood pressure measured at the brachial artery plays a central role in our understanding and management of cardiovascular risk, in recent years great emphasis has been placed on the importance of central blood pressure. It seems straightforward that knowledge of the blood pressure directly affecting the major organs is important for understanding the pathophysiology and treatment of cardiovascular risk. However, the field has been troubled by controversies over measurement techniques and difficulty in designing therapies to modify central but not peripheral blood pressure. In this review, we consider the physiology underlying the change in blood pressure through the arterial tree and how central blood pressure can be measured. In addition, we review the evidence regarding the relationship of central BP to cardiovascular disease and the effects of treatment. New measurement techniques and evidence regarding the specific benefits of therapies in modulating central haemodynamics mean that this is a rapidly developing area, and understanding the concept of central blood pressure will be vital in the future.

Indexed as

Blood PressureAntihypertensive AgentsAortaBlood Pressure DeterminationBrachial ArteryCardiovascular DiseasesHumansHypertensionPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsAntihypertensive Agents

Identifiers

PMID22300350
PMCPMC3630744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.