Evidence map›Paper›PMID 22299658›Full record

ArticleJournal of clinical and experimental neuropsychology2012

Longer ongoing task delay intervals exacerbate prospective memory deficits in HIV-associated neurocognitive disorders (HAND).

Erin E Morgan, Erica Weber, Alexandra S Rooney, Igor Grant, Steven Paul Woods, Hiv Neurobehavioral Research Program Hnrp Group

Abstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Longitudinal declines in event-based, but not time-based, prospective memory among community-dwelling older adults.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Prospective memory in youth with perinatally-acquired HIV infection.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2018
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Time estimation and production in HIV-associated neurocognitive disorders (HAND).Journal of the International Neuropsychological Society : JINS · 2015
    Article
  19. Self-predictions of prospective memory in HIV-associated neurocognitive disorders: evidence of a metamemory deficit.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erin E MorganDepartment of Psychiatry, University of California, San Diego, CA, USA.
Erica Weber
Alexandra S Rooney
Igor Grant
Steven Paul Woods
Hiv Neurobehavioral Research Program Hnrp Group

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Prospective Memory in HIV-1 InfectionR01MH073419 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WOODS, STEVEN PAUL · 2005 to 2017
$6.6M
Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)T32DA031098 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello, DAVID J MOORE · 2011 to 2026
$4.6M
NIAAA NIH HHS T32 AA013525NIAAA NIH HHS T32AA013525NIDA NIH HHS 1T32DA031098NIDA NIH HHS T32 DA031098NIMH NIH HHS 2R01MH073419NIMH NIH HHS P30 MH062512NIMH NIH HHS P30MH62512NIMH NIH HHS R01 MH073419
6 · The paper itself

Abstract

The delay interval between encoding a future intention and detection of the retrieval cue is an essential feature of prospective memory (PM). McDaniel and Einstein's ( 2000 ) multiprocess theory posits that greater demands are placed on strategic monitoring processes as the delay interval lengthens. This hypothesis was examined in HIV-associated neurocognitive disorders (HAND), which are associated with strategic dyscontrol of PM, likely secondary to prefrontostriatal circuit pathology. Seventy-eight seronegative adults and 49 individuals with HAND comprised the study groups, which were comparable with regard to demographic, psychiatric, and substance use factors. As part of a comprehensive neuropsychological evaluation, participants were administered a well-validated PM measure that included short (2-min) and long (15-min) task delay interval scales that utilized a standardized word search as the ongoing task. Results revealed a significant interaction of group and delay interval, with significant effects of HAND on PM at long, but not short, delay. The long-delay PM effect in HAND was driven primarily by deficits in time-based PM and was most strongly associated with markers of executive dysfunction. In concordance with the multiprocess theory, individuals with HAND were disproportionately vulnerable to PM deficits at longer ongoing task delay intervals, which appear to be driven by strategic dyscontrol of PM that is consistent with the preferential disruption of prefrontal systems in neuroAIDS (neurological complications of AIDS). Difficulty with successfully completing PM tasks following a longer delay could manifest in real-world problems, such as medication nonadherence and unemployment, and characterizing this specific deficit may inform remediation strategies.

Indexed as

AdultCognition DisordersFemaleHIV InfectionsHIV SeropositivityHumansMaleMemory DisordersMiddle AgedNeuropsychological Tests

Identifiers

PMID22299658
PMCPMC3311720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.