ArticleThe Journal of biological chemistry2012
Inducible malondialdehyde pools in zones of cell proliferation and developing tissues in Arabidopsis.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 37 citations in OpenAlex.
- The role of stem respiration in cold-acclimation of winter-dormant Quercus robur trees under large air temperature fluctuations.Journal of experimental botany · 2026Article
- Overexpression of the aldehyde dehydrogenaseFrontiers in plant science · 2023Article
- Review of Lipid Biomarkers and Signals of Photooxidative Stress in Plants.Methods in molecular biology (Clifton, N.J.) · 2023Review
- MbICE1 Confers Drought and Cold Tolerance through Up-Regulating Antioxidant Capacity and Stress-Resistant Genes inInternational journal of molecular sciences · 2022Article
- Impact of Geraniol and Geraniol Nanoemulsions onPlants (Basel, Switzerland) · 2022Article
- Ethyl Vinyl Ketone Activates KInternational journal of molecular sciences · 2022Article
- Phytoremediation Potential, Photosynthetic and Antioxidant Response to Arsenic-Induced Stress ofPlants (Basel, Switzerland) · 2020Article
- Malondialdehyde: Facts and Artifacts.Plant physiology · 2019Article
- Aldehyde dehydrogenases may modulate signaling by lipid peroxidation-derived bioactive aldehydes.Plant signaling & behavior · 2017Article
- Membranes as Structural Antioxidants: RECYCLING OF MALONDIALDEHYDE TO ITS SOURCE IN OXIDATION-SENSITIVE CHLOROPLAST FATTY ACIDS.The Journal of biological chemistry · 2016Article
- Durum Wheat Roots Adapt to Salinity Remodeling the Cellular Content of Nitrogen Metabolites and Sucrose.Frontiers in plant science · 2016Article
- Knocking Down of Isoprene Emission Modifies the Lipid Matrix of Thylakoid Membranes and Influences the Chloroplast Ultrastructure in Poplar.Plant physiology · 2015Article
- Priming Salt Resilience in Melon (Cucumis melo) via Pseudomonas oryzihabitans-Mediated Metabolic Reprogramming.Physiologia plantarumArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malondialdehyde (MDA) is a natural and widespread genotoxin. Given its potentially deleterious effects, it is of interest to establish the identities of the cell types containing this aldehyde. We used in situ chemical trapping with 2-thiobarbituric acid and mass spectrometry with a deuterated standard to characterize MDA pools in the vegetative phase in Arabidopsis thaliana. In leaves, MDA occurred predominantly in the intracellular compartment of mesophyll cells and was enriched in chloroplasts where it was derived primarily from triunsaturated fatty acids (TFAs). High levels of MDA (most of which was unbound) were found within dividing cells in the root tip cell proliferation zone. The bulk of this MDA did not originate from TFAs. We confirmed the localization of MDA in transversal root sections. In addition to MDA in proliferating cells near the root tip we found evidence for the presence of MDA in pericyle cells. Remodeling of non-TFA-derived MDA pools occurred when seedlings were infected with the fungus Botrytis cinerea. Treatment of uninfected seedlings with mediators of plant stress responses (jasmonic acid or salicylic acid) increased seedling MDA levels over 20-fold. In summary, major pools of MDA are associated with cell division foci containing stem cells. The aldehyde is pathogen-inducible in these regions and its levels are increased by cellular mediators that impact defense and growth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.