Evidence map›Paper›PMID 22298389›Full record

ArticlePediatric pulmonology2012

Nutritional outcomes following gastrostomy in children with cystic fibrosis.

Gia M Bradley, Kathryn A Carson, Amanda R Leonard, Peter J Mogayzel, Maria Oliva-Hemker

Open access · greenAbstract read
In one paragraph

Article in Pediatric pulmonology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Enteral tube feeding for cystic fibrosis.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Article
  3. Article
  4. Early life growth trajectories in cystic fibrosis are associated with lung function at age six.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Genetic modifiers of nutritional status in cystic fibrosis.The American journal of clinical nutrition · 2012
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gia M BradleyDivision of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kathryn A Carson
Amanda R Leonard
Peter J Mogayzel
Maria Oliva-Hemker
Johns Hopkins University · US

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
Institutional Training for PediatriciansT32HD044355 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BRADY, TAMMY MCLOUGHLIN · 2003 to 2023
$4.1M
NCRR NIH HHS UL1 RR 025005NCRR NIH HHS UL1 RR025005NICHD NIH HHS 5 T32 HD 44355-8NICHD NIH HHS T32 HD044355
6 · The paper itself

Abstract

objectiveIn 2005 the Cystic Fibrosis (CF) Foundation recommended that children with CF maintain a body mass index (BMI) ≥ 50th percentile. Our study evaluated if gastrostomy (GT) placement increases the likelihood of reaching that goal compared to a standardized nutrition protocol. STUDY

designRetrospective study of 20 children with CF ages 2-20 years with GTs placed from 2005 to 2010. Each case was pair-matched on age, sex, pancreatic status, BMI, and lung function with a nonGT child with CF. Outcome measures included nutritional status and lung function at 6 months and 1 year.

resultsAt baseline, mean ± SD BMI Z-scores were similar (cases -1.19 ± 0.60, controls -1.10 ± 0.50; P = 0.10). Cases had a significant 6-month increase in mean BMI Z-score to -0.29 ± 0.84 compared to -1.02 ± 0.67 for controls (P < 0.001). By 1 year, the change in mean BMI Z-score was less different (cases -0.41 ± 0.76, controls -0.71 ± 0.51; P = 0.07). Both groups had stable lung function. From exact logistic regression analysis, the odds ratio for cases compared to controls of reaching BMI ≥ 50th percentile was 9.70 (95% CI: 1.05-484.7; P = 0.04) at 6 months and 3.65 (95%CI: 0.69-25.86; P = 0.16) at 1 year.

conclusionOur study suggests that children with CF who receive GTs are more likely to achieve BMI ≥ 50th percentile than matched children without GTs.

Indexed as

GastrostomyNutritional StatusAdolescentBody Mass IndexCase-Control StudiesChildChild, PreschoolCohort StudiesCystic FibrosisEnteral NutritionFemaleHumansMaleRespiratory Function TestsRetrospective StudiesTreatment Outcome

Identifiers

PMID22298389
PMCPMC3343175
OpenAlexW2160457718

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.